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AntidepressantsAntidepressants

This category covers medicines used for depression, anxiety and some related conditions. They work gradually, often taking two to six weeks for the full effect, and suit treatment alongside support rather than on their own. Dose is usually built up slowly, and the first choice is not always the one a person stays on, so review appointments are part of the treatment.

Lexapro

Escitalopram

5 · 10 · 20mg

Lexapro is escitalopram in 5mg, 10mg and 20mg film-coated tablets for major depression, generalised anxiety and panic disorder. An SSRI.

From$0.51/ tabletView

Paxil

Paroxetine

10 · 20 · 30 · 40mg

Paroxetine tablets from 10mg to 40mg, used in the management of major depression, generalised anxiety and obsessive-compulsive disorder. An SSRI.

From$0.65/ tabletView

Wellbutrin SR

Bupropion

150mg

Wellbutrin SR is bupropion 150mg in a modified-release tablet for tobacco dependence and major depression, a weak reuptake inhibitor of two amines.

From$1.12/ tabletView

Cymbalta

Duloxetine

20 · 30 · 40 · 60mg

Duloxetine prolonged-release capsules from 20mg to 60mg, used in the management of depression, generalised anxiety and diabetic neuropathic pain. An SNRI.

From$0.82/ tabletView

Effexor

Venlafaxine

37.5 · 75mg

Venlafaxine 37.5mg and 75mg, as tablets and prolonged-release capsules, used in the management of major depression and generalised anxiety disorder.

From$0.65/ tabletView

Celexa

Citalopram

10 · 20mg

Citalopram 10mg and 20mg film-coated tablets, used in the management of major depressive disorder. An SSRI that raises serotonin at the synapse.

From$0.53/ tabletView

Trintellix

Vortioxetine

5 · 10 · 20mg

Vortioxetine 5mg, 10mg and 20mg tablets, used in the management of major depressive disorder. A multimodal antidepressant, not a plain SSRI.

From$0.91/ tabletView

Anafranil

Clomipramine

10 · 25 · 50mg

Clomipramine 10mg, 25mg and 50mg film-coated tablets, used in the management of obsessive-compulsive disorder, depression, phobic states and cataplexy.

From$0.56/ tabletView

Zyban

Bupropion

150mg

Bupropion 150mg prolonged-release tablets, used in the management of smoking cessation. It antagonises the nicotinic acetylcholine receptor.

From$1.11/ tabletView

Desyrel

Trazodone

25 · 50 · 100mg

Desyrel is trazodone in 25mg, 50mg and 100mg tablets for major depressive disorder. A SARI, acting at serotonin receptors as well as on reuptake.

From$0.43/ tabletView

Elavil

Amitriptyline

10 · 25 · 50mg

Amitriptyline 10mg, 25mg and 50mg tablets, used in the management of major depression, neuropathic pain and migraine prophylaxis. A tricyclic.

From$0.37/ tabletView

Pamelor

Nortriptyline

25mg

Pamelor is nortriptyline 25mg hard capsules for major depressive disorder, a tricyclic weighted towards noradrenaline reuptake inhibition.

From$0.40/ tabletView

Remeron

Mirtazapine

7.5 · 15 · 30mg

Mirtazapine 7.5mg, 15mg and 30mg tablets, used in the management of major depressive disorder. A NaSSA that antagonises alpha-2 receptors.

From$0.56/ tabletView

Bupron SR

Bupropion

150mg

Bupron SR is bupropion 150mg in a prolonged-release tablet, used in the management of tobacco dependence. A weak noradrenaline and dopamine reuptake inhibitor.

From$1.06/ tabletView

Venlor

Venlafaxine

75mg

Venlor is venlafaxine 75mg tablets for major depressive disorder and generalised anxiety disorder, an SNRI acting on serotonin and noradrenaline.

From$1.00/ tabletView

Luvox

Fluvoxamine

50 · 100mg

Fluvoxamine 50mg and 100mg film-coated tablets, used in the management of obsessive-compulsive disorder and major depression. An SSRI.

From$1.11/ tabletView

Wellbutrin

Bupropion

150 · 300mg

Bupropion 150mg and 300mg modified-release tablets, used in the management of major depression and tobacco dependence. An aminoketone antidepressant.

From$1.06/ tabletView

Paxil CR

Paroxetine

12.5 · 25 · 37.5mg

Paxil CR is paroxetine 12.5mg, 25mg and 37.5mg in a prolonged-release tablet for depression, OCD, panic disorder and social anxiety disorder.

From$1.43/ tabletView

Effexor XR

Venlafaxine

75 · 150mg

Effexor XR is venlafaxine 75mg and 150mg in a prolonged-release capsule for major depression and generalised anxiety disorder. An SNRI taken once a day.

From$0.97/ tabletView

Fludac

Fluoxetine

20mg

Fludac is fluoxetine 20mg hard capsules, used in the management of major depression, obsessive-compulsive disorder and bulimia nervosa. An SSRI.

From$0.61/ tabletView

Sinequan

Doxepin

10 · 25 · 75mg

Doxepin 10mg, 25mg and 75mg hard capsules, used in the management of major depression and anxiety disorder. A tricyclic acting on both amines.

From$0.47/ tabletView

Tofranil

Imipramine

25 · 50 · 75mg

Imipramine 25mg, 50mg and 75mg tablets, used in the management of major depressive disorder and nocturnal enuresis. A tricyclic antidepressant.

From$0.43/ tabletView

Zoloft

Sertraline

25 · 50 · 100mg

Sertraline 25mg, 50mg and 100mg film-coated tablets, used for major depression, obsessive-compulsive disorder, panic disorder and PTSD. An SSRI.

From$0.40/ tabletView

Endep

Amitriptyline

10 · 25 · 50 · 75mg

Amitriptyline film-coated tablets from 10mg to 75mg, used in the management of major depressive disorder and neuropathic pain. A tricyclic antidepressant.

From$0.48/ tabletView

Savella

Milnacipran

25mg

Milnacipran 25mg film-coated tablets, used in the management of fibromyalgia. An SNRI listed for pain rather than for depression.

From$0.85/ tabletView

Key points

  • These medicines work gradually, with the full effect typically taking two to six weeks rather than days.
  • The same classes are used for anxiety as for depression, and some also treat nerve pain.
  • Stopping abruptly can cause withdrawal effects, so changes are tapered under guidance rather than halted.

Classes and ingredients in this category

Conditions it covers

These medicines are used for major depressive disorder, generalised anxiety disorder, obsessive compulsive disorder and panic disorder. The class chosen depends on the diagnosis, other conditions and previous response, none of which a listing can assess.

Further reading