Paxil Cr
Developed to mitigate symptoms of anxiety and depression, this medicine is intended to alleviate emotional distress by balancing mood-regulating neurotransmitters.
- Category
- Antidepressants
- Active ingredient
- Paroxetine
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Prolonged-release tablet
- Strengths
- 12.5 · 25 · 37.5mg
Paxil Cr details
- Conditions
- Major Depressive Disorder · Obsessive-compulsive Disorder · Panic Disorder · Social Anxiety Disorder
- Alternative names
- Seroxat
- Therapeutic class
- Selective Serotonin Reuptake Inhibitor (SSRI)
- Pharmacological class
- SSRI
- Contraindications
- concurrent use of MAO inhibitors; hypersensitivity to paroxetine
- Precautions and warnings
- do not stop taking abruptly; monitor for suicidal thoughts
- Minor side effects
- nausea; drowsiness; dizziness; dry mouth; sweating
- Moderate side effects
- insomnia; sexual dysfunction; tremor
- Dosage forms
- Prolonged-release tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- GSK
- Onset Time
- 2–4 weeks
- Duration
- 24 hours
- Storage instructions
- Store below 25°C in a cool, dry place.
- Drug interactions
- aspirin; ibuprofen; st. john's wort; warfarin
- Age restrictions
- Not typically indicated for patients under 18 years.
Serious side effects
serotonin syndrome, requires immediate medical attention; acute glaucoma, requires immediate medical attention
Patient summary
Developed to mitigate symptoms of anxiety and depression, this medicine is intended to alleviate emotional distress by balancing mood-regulating neurotransmitters.
Mechanism of action
This medication acts as an SSRI. It increases the concentration of serotonin in the synaptic cleft by preventing its reuptake, which helps improve communication between neurons, thereby lifting mood and reducing anxiety levels over time.
Pregnancy and breastfeeding
Pregnancy: Use only if benefits outweigh risks; risk of neonatal complications. Breastfeeding: Small amounts pass into milk; consult your healthcare provider.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Paxil Cr
Paxil Cr is a branded form of paroxetine, used in the treatment of Major Depressive Disorder, Obsessive-compulsive Disorder and Panic Disorder. The same active ingredient is also sold as Seroxat, supplied as a tablet in strengths from 12.5mg to 37.5mg and manufactured by GSK.
Paxil Cr availability in Asia
Paxil Cr is registered across 13 markets including the Philippines, Indonesia and Taiwan, with availability also in South Korea, Japan and the UAE. Generic paroxetine, much of it produced in India, is often more affordable than the original brand for expats and people living across the region. This medication is best used under a doctor’s care.