Anafranil
Utilized to support the management of obsessive-compulsive disorder.
- Category
- Antidepressants
- Active ingredient
- Clomipramine
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 10 · 25 · 50mg
Anafranil details
- Conditions
- Obsessive-compulsive Disorder · Major Depressive Disorder · Phobic States · Cataplexy Associated with Narcolepsy
- Therapeutic class
- Tricyclic Antidepressant
- Pharmacological class
- TCA
- Contraindications
- recent myocardial infarction; maois
- Precautions and warnings
- sedative effects; avoid rapid discontinuation
- Minor side effects
- dry mouth; drowsiness; constipation
- Moderate side effects
- blurred vision; urinary retention; weight gain
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Patient summary
- utilized to support the management of obsessive-compulsive disorder.
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Novartis
- Onset Time
- 2–4 weeks
- Duration
- 24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- alcohol; maois; cimetidine
- Age restrictions
- Use with caution in children.
- Pregnancy and breastfeeding
- Consult doctor before use in pregnancy.
Serious side effects
arrhythmia, requires immediate medical attention; seizures, requires immediate medical attention
Mechanism of action
Clomipramine inhibits the neuronal reuptake of noradrenaline and serotonin, which helps balance neurotransmitter levels to alleviate symptoms.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Anafranil
Anafranil features clomipramine, a treatment indicated for Obsessive-compulsive Disorder, Major Depressive Disorder and Phobic States. Produced by Novartis, the medication is supplied as a tablet in strengths of 10, 25 and 50mg.
Anafranil availability in Asia
Anafranil is registered across 14 markets, including Japan, the UAE and Singapore, with availability also in Hong Kong, Thailand and Malaysia. Generic clomipramine, much of which is manufactured in India, offers a more affordable alternative to the original brand for expats and patients located in areas that may have limited access to specific medications. This treatment should be used under a doctor’s care to monitor its effectiveness.