Paxil

Paroxetine

Developed to address major depressive disorder to alleviate feelings of sadness and anxiety.

Active ingredient
Paroxetine
Supply
Pharmacy
Route
Oral use
Form
Film-coated tablet
Strengths
10 · 20 · 30 · 40mg

Paxil details

Alternative names
Seroxat
Therapeutic class
Selective Serotonin Reuptake Inhibitor (SSRI)
Pharmacological class
SSRI
Known off-label uses
premature ejaculation
Minor side effects
nausea; drowsiness; dry mouth
Moderate side effects
insomnia; sexual dysfunction; weight gain
Dosage forms
Film-coated tablet
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
GSK
Onset Time
1–2 weeks
Duration
24 hours
Storage instructions
Store in a cool, dry place.
Drug interactions
alcohol; monoamine oxidase inhibitors; st. john's wort
Age restrictions
Not recommended for children.
Contraindications

hypersensitivity to paroxetine; concurrent use of monoamine oxidase inhibitors; concurrent use of pimozide

Precautions and warnings

avoid abrupt discontinuation; may impair ability to drive; monitor for changes in mood

Serious side effects

serotonin syndrome, requires immediate medical attention; suicidal ideation, requires immediate medical attention

Patient summary

Developed to address major depressive disorder to alleviate feelings of sadness and anxiety.

Mechanism of action

Inhibits the reuptake of serotonin in the brain, which increases the availability of this neurotransmitter to improve mood and emotional regulation.

Pregnancy and breastfeeding

Pregnancy: Use under medical supervision only if benefits outweigh risks. Breastfeeding: Excreted in breast milk; consult your doctor.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Paxil

Paxil is a well-known brand of paroxetine, used to manage Major Depressive Disorder, Generalized Anxiety Disorder and Obsessive-compulsive Disorder. This active ingredient is also marketed under the brand name Seroxat. It is supplied as a tablet in strengths of 10, 20, 30 and 40mg. Manufactured by GSK, this medication provides support for these identified mental health conditions.

Paxil availability in Asia

Paxil is registered across 13 markets, including Malaysia, the Philippines and Indonesia, with availability also in Taiwan, South Korea and Japan. Generic paroxetine, much of it made in India, is far more affordable than the original brand, providing a practical option for expats and people living in regions far from a well-stocked pharmacy. As this medication is used for complex conditions, it is best used under a doctor’s care.