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Cymbalta
AntidepressantsNeurology

Cymbalta

Duloxetine

Duloxetine prolonged-release capsules from 20mg to 60mg, used in the management of depression, generalised anxiety and diabetic neuropathic pain. An SNRI.

Categories
Antidepressants · Neurology
Active ingredient
Duloxetine
Route
Oral use
Form
Prolonged-release capsule, hard
Strengths
20 · 30 · 40 · 60mg

You will receive a quality generic equivalent, depending on stock.

Prescription rules on Cymbalta vary by country.

Cymbalta details

Conditions
Major Depressive Disorder · Generalised Anxiety Disorder · Diabetic Peripheral Neuropathic Pain
Alternative names
Yentreve; Duzela
Therapeutic class
Serotonin-Norepinephrine Reuptake Inhibitor (SNRI)
Pharmacological class
SNRI
Contraindications
uncontrolled narrow-angle glaucoma; concurrent use of MAO inhibitors
Precautions and warnings
monitor for suicidal ideation; may impair alertness
Minor side effects
nausea; dry mouth
Moderate side effects
insomnia; dizziness; somnolence
Dosage forms
Prolonged-release capsule, hard
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Originator
Eli Lilly
Onset Time
1–2 weeks
Duration
24 hours
Storage instructions
Store below 25°C in a dry place.
Drug interactions
alcohol; st. john's wort
Pregnancy and breastfeeding
Pregnancy: consult specialist. Breastfeeding: discuss with physician.
Serious side effects

serotonin syndrome, requires immediate medical attention; hepatitis, requires immediate medical attention

Patient summary

Duloxetine prolonged-release capsules from 20mg to 60mg, used in the management of depression, generalised anxiety and diabetic neuropathic pain. An SNRI.

Mechanism of action

it inhibits the neuronal uptake of serotonin and norepinephrine, resulting in increased levels of these neurotransmitters in the synaptic cleft.

What you will receive

Cymbalta is the originator brand name, made by Eli Lilly. We use it here to identify the medicine only; we are not affiliated with Eli Lilly and do not ship the original Cymbalta.

  • You receive a generic equivalent: the same active ingredient (Duloxetine) at the same dose, mostly recognised Indian branded generics from vetted manufacturers.
  • The exact brand supplied depends on what is in stock at the dispatching warehouse.
  • A regulated generic matches the original ingredient for ingredient by legal standard.

Are all generics really the same? Read the honest answer.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Cymbalta

Cymbalta is the primary brand name for duloxetine, a medication used to treat Major Depressive Disorder, Generalised Anxiety Disorder and diabetic peripheral neuropathic pain. The same active ingredient is also sold under names such as Yentreve and Duzela. It is manufactured as a tablet in strengths ranging from 20mg to 60mg.

Cymbalta availability in Asia

Cymbalta is registered across 14 markets including Indonesia, Taiwan and South Korea, with availability also in Japan, the UAE and Singapore. While the original brand remains a standard, generic duloxetine is often more affordable for patients living or working far from home. As this medication manages complex symptoms, it is best used under the ongoing care of a doctor.