Cymbalta
Formulated to manage major depressive disorder to support mental wellness.
- Categories
- Antidepressants · Neurology
- Active ingredient
- Duloxetine
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Prolonged-release capsule, hard
- Strengths
- 20 · 30 · 40 · 60mg
Cymbalta details
- Conditions
- Major Depressive Disorder · Generalized Anxiety Disorder · Diabetic Peripheral Neuropathic Pain
- Alternative names
- Yentreve; Duzela
- Therapeutic class
- Serotonin-Norepinephrine Reuptake Inhibitor (SNRI)
- Pharmacological class
- SNRI
- Contraindications
- uncontrolled narrow-angle glaucoma; concurrent use of MAO inhibitors
- Precautions and warnings
- monitor for suicidal ideation; may impair alertness
- Minor side effects
- nausea; dry mouth
- Moderate side effects
- insomnia; dizziness; somnolence
- Dosage forms
- Prolonged-release capsule, hard
- Administration route
- Oral use
- Patient summary
- formulated to manage major depressive disorder to support mental wellness.
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Eli Lilly
- Onset Time
- 1–2 weeks
- Duration
- 24 hours
- Storage instructions
- Store below 25°C in a dry place.
- Drug interactions
- alcohol; st. john's wort
- Pregnancy and breastfeeding
- Pregnancy: consult specialist. Breastfeeding: discuss with physician.
Serious side effects
serotonin syndrome, requires immediate medical attention; hepatitis, requires immediate medical attention
Mechanism of action
it inhibits the neuronal uptake of serotonin and norepinephrine, resulting in increased levels of these neurotransmitters in the synaptic cleft.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Cymbalta
Cymbalta is the primary brand name for duloxetine, a medication used to treat Major Depressive Disorder, Generalized Anxiety Disorder and diabetic peripheral neuropathic pain. The same active ingredient is also sold under names such as Yentreve and Duzela. It is produced by Eli Lilly and manufactured as a tablet in strengths ranging from 20mg to 60mg.
Cymbalta availability in Asia
Cymbalta is registered across 14 markets including Indonesia, Taiwan and South Korea, with availability also in Japan, the UAE and Singapore. While the original brand remains a standard, generic duloxetine is often more affordable for patients living or working far from home. As this medication manages complex symptoms, it is best used under the ongoing care of a doctor.