Elavil
Designed for effective depressive symptoms management and utilized to support mood stability in patients.
- Categories
- Antidepressants · Neurology
- Active ingredient
- Amitriptyline
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Tablet; Film-coated tablet
- Strengths
- 10 · 25 · 50mg
Elavil details
- Conditions
- Major Depressive Disorder · Neuropathic Pain · Migraine Prophylaxis
- Alternative names
- Tryptizol
- Therapeutic class
- Tricyclic Antidepressant (TCA)
- Pharmacological class
- TCA
- Known off-label uses
- tension-type headache
- Minor side effects
- dry mouth; sedation; dizziness; constipation
- Moderate side effects
- urinary retention; blurred vision; weight gain; tachycardia
- Dosage forms
- Tablet; Film-coated tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- AstraZeneca
- Onset Time
- 2–4 weeks
- Duration
- 24 hours
- Storage instructions
- Store in a cool, dry place.
- Drug interactions
- Alcohol; MAO inhibitors; Cimetidine
- Age restrictions
- Not for use in children and adolescents.
Contraindications
recent myocardial infarction; heart block; arrhythmia; severe liver impairment; mania
Precautions and warnings
may impair ability to drive or operate machinery; use with caution in elderly patients; may affect blood sugar control
Serious side effects
cardiac arrhythmia, requires immediate medical attention; convulsions, requires immediate medical attention; paralytic ileus, requires immediate medical attention
Patient summary
Designed for effective depressive symptoms management and utilized to support mood stability in patients.
Mechanism of action
This medicine acts by increasing the concentration of neurotransmitters like serotonin and noradrenaline in the synaptic cleft by inhibiting their reuptake into nerve terminals, thereby enhancing mood and providing pain-relieving effects.
Pregnancy and breastfeeding
Pregnancy: Not recommended. Breastfeeding: Small amounts excreted in milk; monitor infant.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Elavil
Elavil is the well-known brand of Amitriptyline, a medication utilised for Major Depressive Disorder, neuropathic pain and migraine prophylaxis. The same active ingredient is also sold under the brand Tryptizol. Produced by AstraZeneca, the medication is supplied as a tablet in strengths of 10, 25 and 50mg.
Elavil availability in Asia
Elavil is registered across 14 markets including Japan, the UAE and Singapore, with availability also in Hong Kong, Thailand and Malaysia. Accessing generic Amitriptyline, often manufactured in India, provides a more affordable alternative to the original brand for expats and those located far from a well-stocked pharmacy. Such treatment options assist in consistent symptom management across the region and are best used under a doctor’s care.