Depakene
Formulated to manage epilepsy and bipolar disorder, this medication is indicated to support the control of seizures and is utilized to mitigate mood fluctuations.
- Category
- Neurology
- Active ingredient
- Valproic Acid
- Supply
- Rx
- Route
- Oral use
- Form
- Capsule, soft
- Strengths
- 250 · 750mg
Depakene details
- Conditions
- Epilepsy · Bipolar Disorder · Migraine Prophylaxis
- Alternative names
- Epilim; Depakote
- Therapeutic class
- Antiepileptic
- Pharmacological class
- Valproate
- Contraindications
- hepatic impairment; urea cycle disorders; pregnancy; porphyria
- Minor side effects
- nausea; tremor; dizziness; somnolence
- Moderate side effects
- weight gain; hair loss; oedema
- Dosage forms
- Capsule, soft
- Administration route
- Oral use
- Supply category
- Prescription only (specially controlled medicine)
- Manufacturer
- Abbott
- Onset Time
- 1–4 weeks
- Duration
- 24 hours
- Storage instructions
- Store at room temperature.
- Drug interactions
- alcohol; phenobarbital; carbamazepine; rifampicin
- Age restrictions
- Use with caution in children.
Precautions and warnings
monitor liver function; monitor for signs of depression; avoid rapid discontinuation
Serious side effects
hepatotoxicity, requires immediate medical attention; pancreatitis, requires immediate medical attention; thrombocytopenia, requires immediate medical attention
Patient summary
Formulated to manage epilepsy and bipolar disorder, this medication is indicated to support the control of seizures and is utilized to mitigate mood fluctuations.
Mechanism of action
Valproic acid increases the concentration of gamma-aminobutyric acid (GABA) in the brain, thereby inhibiting excessive neuronal activity and reducing seizure frequency.
Pregnancy and breastfeeding
Pregnancy: Contraindicated; high risk of malformations. Breastfeeding: Consult a physician.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Depakene
Depakene contains valproic acid, an active ingredient used for the management of epilepsy, bipolar disorder and migraine prophylaxis. This medication is also sold under brand names such as Epilim and Depakote, supplied as a capsule in strengths of 250mg and 750mg. Manufactured by Abbott, it remains a standard option for patients requiring this specific treatment.
Buying Depakene online
Depakene is registered across 13 markets including South Korea, Japan and the UAE, with availability also in Singapore, Hong Kong and Thailand. Generic valproic acid, much of it made in India, is far more affordable than the original brand. For expats and people based far from a well stocked pharmacy, this medication is one of the most ordered items in our store across the region.