Lamictal

Lamotrigine

Developed as an antiepileptic agent, this medication is designed to target seizure activity to alleviate frequency in patients with neurological conditions.

Category
Neurology
Active ingredient
Lamotrigine
Supply
Rx
Route
Oral use
Form
Tablet; Dispersible tablet
Strengths
25 · 50 · 100 · 200mg

Lamictal details

Therapeutic class
Antiepileptic
Pharmacological class
Phenyltriazine
Contraindications
hypersensitivity to lamotrigine
Minor side effects
headache; dizziness; nausea; somnolence
Moderate side effects
diplopia; blurred vision; ataxia
Dosage forms
Tablet; Dispersible tablet
Administration route
Oral use
Supply category
Prescription only (specially controlled medicine)
Manufacturer
GSK
Onset Time
1–3 hours
Duration
24–36 hours
Storage instructions
Store at room temperature in a dry place.
Drug interactions
valproate; carbamazepine; phenytoin; hormonal contraceptives
Age restrictions
Not recommended for children under 2 years.
Precautions and warnings

risk of serious skin rashes; monitor for signs of hypersensitivity; advise avoiding abrupt discontinuation

Serious side effects

stevens-johnson syndrome, requires immediate medical attention; toxic epidermal necrolysis, requires immediate medical attention; haemophagocytic lymphohistiocytosis, requires immediate medical attention

Patient summary

Developed as an antiepileptic agent, this medication is designed to target seizure activity to alleviate frequency in patients with neurological conditions.

Mechanism of action

Lamotrigine stabilizes neuronal membranes by inhibiting voltage-gated sodium channels, which limits the release of excitatory neurotransmitters like glutamate. This mechanism supports control of seizure thresholds and mood stabilisation.

Pregnancy and breastfeeding

Pregnancy: Use with caution as risks to the foetus are currently being evaluated. Breastfeeding: Small amounts pass into breast milk; monitoring is recommended.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Lamictal

Lamictal acts as an established brand of lamotrigine, a medication used in the management of epilepsy and bipolar disorder. Produced by GSK, these tablets are available in strengths of 25, 50, 100, and 200mg. Patients often rely on this option for consistent maintenance therapy to manage their conditions.

Buying Lamictal online

Lamictal is registered across 14 markets, including Thailand, Malaysia and the Philippines, with availability also in Indonesia, Taiwan and South Korea. As one of the most ordered products across the region, this medication helps expats and local residents when finding consistent stock proves difficult. Generic lamotrigine, much of which is made in India, provides a more affordable alternative to the original brand for ongoing treatment.