Valparin
Utilized to manage seizures and stabilize mood, formulated to target neurological hyperexcitability and support better physiological function in patients.
- Category
- Neurology
- Active ingredient
- Valproic Acid
- Supply
- Rx
- Route
- Oral use
- Form
- Tablet
- Strengths
- 250 · 500 · 750mg
Valparin details
- Conditions
- Epilepsy · Bipolar Disorder · Migraine Prophylaxis
- Alternative names
- Epilim; Depakote
- Therapeutic class
- Antiepileptic
- Pharmacological class
- Carboxylic acid
- Known off-label uses
- neuropathic pain
- Minor side effects
- nausea; tremor; drowsiness
- Moderate side effects
- weight gain; alopecia; thrombocytopenia
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription only (specially controlled medicine)
- Manufacturer
- Sun Pharma
- Onset Time
- 1–4 weeks
- Duration
- 12–24 hours
- Storage instructions
- Store in a cool, dry place away from direct sunlight.
- Drug interactions
- Alcohol; carbamazepine; phenytoin; aspirin
- Age restrictions
- Use with caution in children and adolescents; monitor for hepatotoxicity.
Contraindications
hypersensitivity to valproic acid; active liver disease; history of severe hepatic impairment; urea cycle disorders; porphyria; pregnancy
Precautions and warnings
regular monitoring of liver function required; may impair ability to drive or operate machinery
Serious side effects
hepatotoxicity, requires immediate medical attention; pancreatitis, requires immediate medical attention; anaphylaxis, requires immediate medical attention
Patient summary
Utilized to manage seizures and stabilize mood, formulated to target neurological hyperexcitability and support better physiological function in patients.
Mechanism of action
Valproic acid increases the concentration of gamma-aminobutyric acid (GABA) in the brain. It also blocks voltage-gated sodium channels and T-type calcium channels, stabilizing nerve membranes and reducing excessive electrical activity associated with convulsions and mood dysregulation.
Pregnancy and breastfeeding
Valproic acid must not be used during pregnancy due to high risk of birth defects and developmental disorders. Effective contraception is essential.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Valparin
Valparin is a brand of valproic acid, used to manage epilepsy, bipolar disorder and migraine prophylaxis. The same active ingredient is sold under names like Epilim and Depakote. Manufactured by Sun Pharma, Valparin is supplied as a tablet in strengths of 250, 500 and 750mg.
Buying Valparin online
Valparin is registered across 13 markets including Singapore, Hong Kong and Thailand, with further availability in Malaysia, the Philippines and Indonesia. Generic valproic acid is often more affordable than the original brand, and many people living across the region order it online for consistent access. This reach helps expats and residents who are far from a well-stocked pharmacy maintain their treatment routine.