Depakote
Indicated to manage seizures and moods.
- Category
- Neurology
- Active ingredient
- Valproic Acid
- Supply
- Rx
- Route
- Oral use
- Form
- Gastro-resistant tablet
- Strengths
- 125 · 250 · 500mg
Depakote details
- Conditions
- Epilepsy · Bipolar Disorder
- Alternative names
- Epilim
- Therapeutic class
- Antiepileptic
- Pharmacological class
- Histone deacetylase inhibitor
- Known off-label uses
- migraine prophylaxis
- Contraindications
- hepatic impairment; urea cycle disorders; porphyria
- Precautions and warnings
- regular blood count monitoring recommended; may cause liver toxicity
- Minor side effects
- nausea; tremor; somnolence
- Moderate side effects
- ataxia; weight gain; alopecia
- Dosage forms
- Gastro-resistant tablet
- Administration route
- Oral use
- Patient summary
- indicated to manage seizures and moods.
- Supply category
- Prescription only (specially controlled medicine)
- Manufacturer
- AbbVie
- Onset Time
- 1–2 weeks
- Duration
- 12–24 hours
- Storage instructions
- Store in a cool, dry place.
- Drug interactions
- aspirin; warfarin; phenytoin
Serious side effects
pancreatitis, requires immediate medical attention; hepatotoxicity, requires immediate medical attention
Mechanism of action
Valproate acts by increasing the concentration of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the brain, which stabilizes electrical activity and balances mood regulation.
Age restrictions
High risk in pregnancy (avoid in females of childbearing potential unless no other treatment is effective).
Pregnancy and breastfeeding
Pregnancy: Strictly contraindicated due to risk of birth defects. Breastfeeding: Generally not recommended.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Depakote
Depakote is a widely used brand formulation of Valproic Acid, a treatment commonly applied for Epilepsy and Bipolar Disorder. This medication is also known by the brand Epilim and is produced by AbbVie. It is supplied as a tablet in strengths ranging from 125mg to 500mg to suit individual patient requirements.
Buying Depakote online
Depakote is registered across 13 markets including Japan, the UAE and Singapore, with availability extending to Hong Kong, Thailand and Malaysia. Accessing Valproic Acid online provides a reliable alternative for expats and residents across the region. Generic versions of this medication often cost significantly less than the original brand while maintaining the same active chemical profile, making this one of the most ordered items for patients needing consistent access to their medicine.