Skip to content

Epilepsy

Epilepsy is a chronic neurological condition in which the brain periodically produces bursts of abnormal electrical activity, triggering seizures. It affects roughly 50 million people worldwide.

Neurontin

Gabapentin

100 · 300 · 400 · 600mg

Gabapentin hard capsules from 100mg to 600mg, used in the management of epilepsy and neuropathic pain. A structural analogue of GABA.

From$0.43/ tabletView

Lamictal

Lamotrigine

25 · 50 · 100 · 200mg

Lamotrigine 25mg to 200mg, as plain and dispersible tablets, used in the management of epilepsy and bipolar disorder. It blocks voltage-gated sodium channels.

From$0.86/ tabletView

Topamax

Topiramate

25 · 50 · 100mg

Topiramate 25mg, 50mg and 100mg film-coated tablets, used in the management of epilepsy and migraine prophylaxis. It acts on several channels at once.

From$0.68/ tabletView

Trileptal

Oxcarbazepine

150 · 300 · 600mg

Oxcarbazepine 150mg, 300mg and 600mg film-coated tablets, used in the management of epilepsy. It blocks voltage-sensitive sodium channels.

From$0.67/ tabletView

Depakote

Valproic Acid

125 · 250 · 500mg

Valproic acid 125mg, 250mg and 500mg gastro-resistant tablets, used in the management of epilepsy and bipolar disorder. GABA levels rise under it.

From$0.28/ tabletView

Valparin

Valproic Acid

250 · 500 · 750mg

Valparin is valproic acid 250mg, 500mg and 750mg tablets for epilepsy, bipolar disorder and migraine prophylaxis. GABA rises, sodium channels close.

From$3.06/ tabletView

Tegretol

Carbamazepine

100 · 200 · 400mg

Carbamazepine 100mg, 200mg and 400mg tablets, used in the management of epilepsy and trigeminal neuralgia. It blocks voltage-gated sodium channels.

From$0.48/ tabletView

Mysoline

Primidone

250mg

Primidone 250mg tablets, used in the management of epilepsy. A barbiturate metabolised to phenobarbital and phenylethylmalonamide.

From$0.88/ tabletView

Depakene

Valproic Acid

250 · 750mg

Valproic acid 250mg and 750mg soft capsules, used in the management of epilepsy, bipolar disorder and migraine prophylaxis. It raises GABA in the brain.

From$2.13/ capsuleView

Divalproex Tablets

Divalproex

125 · 250 · 500mg

Divalproex 125mg, 250mg and 500mg prolonged-release tablets, used in the management of epilepsy and bipolar disorder. Sodium valproate with valproic acid.

From$0.28/ tabletView

Key points

  • Abnormal electrical activity firing in the brain triggers seizures that vary widely in how they present.
  • Seizure types range from convulsive episodes with loss of consciousness to brief blank spells typical in childhood or disturbances confined to one brain region.
  • Valproic acid has long been among the oldest, broadly effective anticonvulsants, while lamotrigine and oxcarbazepine are often chosen for focal epilepsy.
  • Sleep deprivation, alcohol and flickering light are among the recognised triggers, and taking medicine at consistent times matters as much as the specific drug chosen.

What seizures look like

Seizures vary widely. Generalised tonic-clonic seizures involve loss of consciousness and convulsions; absence seizures are brief blank episodes, most common in children; focal seizures start in one brain region and may or may not spread. Many people have a warning sign called an aura, such as an unusual smell, visual disturbance, or rising feeling in the abdomen, in the seconds before a seizure begins.

Medicines used in epilepsy

Most people with epilepsy achieve good seizure control with a single anticonvulsant. Valproic acid is one of the oldest and most broadly effective agents, used across many seizure types. Lamotrigine and oxcarbazepine are frequently chosen for focal epilepsy and are generally well tolerated. Topiramate works for both focal and generalised seizures. Gabapentin and primidone address specific seizure patterns. Ongoing treatment decisions belong with a neurology specialist, who will weigh seizure type, age, and individual response.

Living with epilepsy day to day

Consistent medicine timing matters as much as dose. Common triggers include sleep deprivation, alcohol, fever, and intense flickering light. Many people with controlled epilepsy drive, work, and travel normally, though local regulations on driving with epilepsy vary by country, so checking national rules is worthwhile.

If a generalised seizure lasts more than five minutes or a person does not regain consciousness between seizures, call emergency services immediately.

Further reading