Trintellix
Intended to treat major depressive disorder and designed to support emotional stability.
- Category
- Antidepressants
- Active ingredient
- Vortioxetine
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Tablet
- Strengths
- 5 · 10 · 20mg
Trintellix details
- Condition
- Major Depressive Disorder
- Alternative names
- Brintellix
- Therapeutic class
- Antidepressant
- Pharmacological class
- Multimodal Antidepressant
- Contraindications
- hypersensitivity to vortioxetine; concurrent use of MAO inhibitors
- Precautions and warnings
- monitor for suicidal thoughts especially in young adults; do not stop abruptly
- Minor side effects
- nausea; constipation; vomiting
- Moderate side effects
- dizziness; pruritus; night sweats
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Lundbeck
- Onset Time
- 2–4 weeks
- Duration
- 24 hours
- Storage instructions
- Store at room temperature below 30°C.
- Drug interactions
- MAO inhibitors; SSRIs; Alcohol
- Age restrictions
- Not recommended for children and adolescents under 18.
Serious side effects
serotonin syndrome, requires immediate medical attention; hyponatraemia, requires immediate medical attention
Patient summary
Intended to treat major depressive disorder and designed to support emotional stability.
Mechanism of action
Trintellix is a multimodal antidepressant that inhibits serotonin reuptake while modulating several serotonin receptor subtypes to help balance neurotransmitter activity in the brain.
Pregnancy and breastfeeding
Pregnancy: Use only if clearly needed. Breastfeeding: Use with caution as risk to infant cannot be excluded.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Trintellix
Trintellix contains the active ingredient vortioxetine and is used for the management of Major Depressive Disorder. The same medication is often sold under the brand name Brintellix. Produced by Lundbeck, it comes as a tablet in 5, 10, and 20mg strengths to assist patients in maintaining their mental health.
Trintellix availability in Asia
Trintellix is registered across 13 markets, including Japan, the UAE and Singapore, with availability also in Hong Kong, Thailand and Malaysia. Generic vortioxetine, much of it made in India, is often more affordable than the original brand. For expats living far from consistent medical support, accessing this medication remains an important consideration. As with all therapies for mental health, this medicine is best used under a doctor’s care, allowing for regular monitoring of individual progress and health needs.