Wellbutrin Sr
Indicated to address nicotine dependence, intended to mitigate withdrawal symptoms and support cessation efforts.
- Categories
- Antidepressants · Addiction Recovery
- Active ingredient
- Bupropion
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Modified-release tablet
- Strengths
- 150mg
Wellbutrin Sr details
- Conditions
- Tobacco Dependence · Major Depressive Disorder
- Alternative names
- Zyban; Wellbutrin
- Therapeutic class
- Smoking Cessation Aid; Antidepressant
- Pharmacological class
- Aminoketone
- Minor side effects
- dry mouth; insomnia; headache; nausea
- Moderate side effects
- tremor; anxiety; dizziness
- Dosage forms
- Modified-release tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- GSK
- Onset Time
- 1–2 weeks
- Duration
- 7–12 weeks
- Storage instructions
- Store below 25°C in original packaging.
- Drug interactions
- alcohol; MAO inhibitors; levodopa
- Age restrictions
- Not for use in individuals under 18 years.
Contraindications
hypersensitivity to bupropion; seizure disorder; bulimia or anorexia nervosa; severe hepatic cirrhosis; current or prior use of monoamine oxidase inhibitors
Precautions and warnings
risk of seizure is dose-dependent; avoid abrupt discontinuation; monitor for neuropsychiatric symptoms
Serious side effects
seizure, requires immediate medical attention; angioedema, requires immediate medical attention
Patient summary
Indicated to address nicotine dependence, intended to mitigate withdrawal symptoms and support cessation efforts.
Mechanism of action
Bupropion is a relatively weak inhibitor of the neuronal uptake of serotonin and norepinephrine and inhibits the neuronal uptake of dopamine. Its mechanism in smoking cessation is not fully elucidated but involves noradrenergic and dopaminergic pathways.
Pregnancy and breastfeeding
Pregnancy: Use with caution only if benefit outweighs risk. Breastfeeding: Not recommended due to excretion in breast milk.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Wellbutrin Sr
Wellbutrin Sr contains bupropion, an active ingredient used to assist with the management of tobacco dependence and major depressive disorder. Other versions of this ingredient are sold under brand names such as Zyban and Wellbutrin. Manufactured by GSK, this treatment is provided as a 150mg tablet.
Wellbutrin Sr availability in Asia
Wellbutrin Sr is registered across 11 markets including Malaysia, the Philippines and Taiwan, with availability also in South Korea, the UAE and Singapore. Generic bupropion often costs less than the original brand, offering an efficient approach for expats and individuals situated far from a reliably stocked local pharmacy. This type of treatment is best used under a doctor’s care.