Zyban
Designed to support smoking cessation, utilized to relieve nicotine withdrawal and reduce the urge to smoke.
- Categories
- Antidepressants · Addiction Recovery
- Active ingredient
- Bupropion
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Prolonged-release tablet
- Strengths
- 150mg
Zyban details
- Condition
- Smoking Cessation
- Alternative names
- Wellbutrin
- Therapeutic class
- Smoking Cessation Aid
- Pharmacological class
- Aminoketone
- Known off-label uses
- major depressive disorder
- Precautions and warnings
- caution in patients with a history of head trauma; may cause dizziness
- Minor side effects
- insomnia; dry mouth; nausea
- Moderate side effects
- anxiety; tremor; dizziness; fever
- Dosage forms
- Prolonged-release tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- GSK
- Onset Time
- 1–2 weeks
- Duration
- 7–9 weeks
- Storage instructions
- Store at room temperature in a dry place.
- Drug interactions
- alcohol; MAO inhibitors; citalopram
- Age restrictions
- Not recommended for those under 18 years.
- Pregnancy and breastfeeding
- Use only if necessary; consult a physician.
Contraindications
hypersensitivity to bupropion; seizure disorders; eating disorders; concurrent use of MAO inhibitors
Serious side effects
seizures, requires immediate medical attention; anaphylaxis, requires immediate medical attention
Patient summary
Designed to support smoking cessation, utilized to relieve nicotine withdrawal and reduce the urge to smoke.
Mechanism of action
This medicine acts as a non-competitive antagonist of the nicotinic acetylcholine receptor. It also inhibits the neuronal reuptake of norepinephrine and dopamine, though the exact mechanism for assisting smoking cessation is likely related to its noradrenergic and dopaminergic effects.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Zyban
Zyban contains bupropion, an ingredient used to support smoking cessation. This medication is also sold under its well-known brand name, Wellbutrin, and is supplied as a tablet in a 150mg strength. Manufactured by GSK, this option provides a consistent formulation for those seeking assistance with their smoking cessation goals.
Zyban availability in Asia
Zyban is registered across 12 markets including Hong Kong, Thailand and Malaysia, with availability also in the Philippines, Taiwan and South Korea. Generic bupropion, much of it made in India, is far more affordable than the original brand, making it a practical option for expats and those living in regions where local clinical options may be limited or costly. As with any approach to smoking cessation, this medication is best used under the guidance of a doctor.