Champix

Varenicline

Designed to manage nicotine addiction and indicated to support smoking cessation by mitigating cravings and relieving withdrawal discomfort during treatment.

Active ingredient
Varenicline
Supply
Rx
Route
Oral use
Form
Film-coated tablet
Strengths
0.5 · 1mg

Champix details

Therapeutic class
Smoking Cessation Aid
Pharmacological class
Nicotinic Receptor Partial Agonist
Contraindications
hypersensitivity to varenicline
Precautions and warnings
monitor for neuropsychiatric symptoms; caution with alcohol intake
Minor side effects
nausea; insomnia
Moderate side effects
vivid dreams; headache
Dosage forms
Film-coated tablet
Administration route
Oral use
Supply category
Prescription only (specially controlled medicine)
Manufacturer
Pfizer
Onset Time
1–2 weeks
Duration
12 weeks
Storage instructions
Store below 30°C.
Drug interactions
nicotine replacement therapy
Age restrictions
18 years and older.
Pregnancy and breastfeeding
Not recommended during pregnancy.
Serious side effects

suicidal ideation, requires immediate medical attention; depression, requires immediate medical attention

Patient summary

Designed to manage nicotine addiction and indicated to support smoking cessation by mitigating cravings and relieving withdrawal discomfort during treatment.

Mechanism of action

Varenicline acts as a partial agonist at alpha-4-beta-2 nicotinic acetylcholine receptors. It stimulates these receptors to relieve nicotine withdrawal cravings while simultaneously blocking nicotine from binding to them, which reduces the reinforcing effects of smoking.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Champix

Champix contains Varenicline, an active ingredient widely used for Smoking Cessation. Manufactured by Pfizer and supplied as a tablet in strengths of 0.5mg and 1mg, the therapy aims to reduce withdrawal symptoms and the gratification associated with tobacco use. Many individuals find the regimen helpful for managing physical cravings during the cessation process.

Champix availability in Asia

Champix is registered across 14 markets including Singapore, Hong Kong and Thailand, with availability also in Malaysia, the Philippines and Indonesia. While the original brand is well recognised, generic Varenicline, often manufactured in India, provides a more affordable price point for expats and people residing far from a well-stocked pharmacy. As with any medication, this is best utilised under the guidance of a doctor to ensure appropriate care.