Pamelor
Indicated to alleviate depressive episodes and utilized to support mood stabilization in patients.
- Category
- Antidepressants
- Active ingredient
- Nortriptyline
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Capsule, hard
- Strengths
- 25mg
Pamelor details
- Condition
- Major Depressive Disorder
- Alternative names
- Allegron
- Therapeutic class
- Tricyclic Antidepressant (TCA)
- Pharmacological class
- TCA
- Known off-label uses
- neuropathic pain; enuresis
- Contraindications
- recent myocardial infarction; arrhythmia; mania; severe liver impairment
- Precautions and warnings
- may cause drowsiness; monitor pulse in elderly patients
- Minor side effects
- dry mouth; sedation; constipation; dizziness
- Moderate side effects
- blurred vision; urinary retention; tachycardia; weight gain
- Dosage forms
- Capsule, hard
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Amdipharm
- Onset Time
- 2–4 weeks
- Duration
- 24 hours
- Storage instructions
- Store in a cool, dry place.
- Drug interactions
- Alcohol; MAO inhibitors; Cimetidine
- Age restrictions
- Not recommended for children.
- Pregnancy and breastfeeding
- Pregnancy: Use only if clearly indicated. Breastfeeding: Exercise caution.
Serious side effects
arrhythmia, requires immediate medical attention; suicidal ideation, requires immediate medical attention; convulsions, requires immediate medical attention
Patient summary
Indicated to alleviate depressive episodes and utilized to support mood stabilization in patients.
Mechanism of action
Utilizes a balanced reuptake inhibition of noradrenaline to lift mood and improve energy levels, acting as a secondary amine tricyclic antidepressant with an improved tolerance profile compared to other TCAs.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Pamelor
Pamelor contains nortriptyline, a medication used to help manage symptoms of Major Depressive Disorder. The same active ingredient is also sold under other names like Allegron, supplied as a tablet in a 25mg strength. Manufactured by Amdipharm, it is an established treatment option for those seeking relief from depression symptoms.
Pamelor availability in Asia
Pamelor is registered across 13 markets including Hong Kong, Thailand and Malaysia, with availability also in the Philippines, Indonesia and Taiwan. Generic nortriptyline, much of it made in India, is far more affordable than the original brand, providing an accessible option for expats and people living at a distance from a well-stocked pharmacy. As with any mental health treatment, this medication is best used under a doctor’s guidance.