Remeron
This medication is indicated for major depressive disorder and utilized to manage associated symptoms such as sleep disturbance and loss of appetite.
- Category
- Antidepressants
- Active ingredient
- Mirtazapine
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Tablet
- Strengths
- 7.5 · 15 · 30mg
Remeron details
- Condition
- Major Depressive Disorder
- Alternative names
- Zispin
- Therapeutic class
- Tetracyclic Antidepressant
- Pharmacological class
- Noradrenergic and Specific Serotonergic Antidepressant (NaSSA)
- Known off-label uses
- generalized anxiety disorder; insomnia
- Contraindications
- hypersensitivity to mirtazapine; concurrent use of MAO inhibitors
- Minor side effects
- drowsiness; increased appetite; weight gain; dry mouth
- Moderate side effects
- dizziness; oedema
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Organon
- Onset Time
- 1–2 weeks
- Duration
- 6–12 months
- Storage instructions
- Store below 30°C in the original packaging.
- Drug interactions
- Alcohol; Benzodiazepines; MAO inhibitors
- Age restrictions
- Caution in elderly patients.
Precautions and warnings
may impair ability to drive or operate machinery; monitor for worsening depression or suicidal ideation
Serious side effects
agranulocytosis, requires immediate medical attention; seizures, requires immediate medical attention
Patient summary
This medication is indicated for major depressive disorder and utilized to manage associated symptoms such as sleep disturbance and loss of appetite.
Mechanism of action
Mirtazapine enhances central noradrenergic and serotonergic activity by antagonizing alpha-2-adrenergic receptors and serotonin 5-HT2 and 5-HT3 receptors. This mechanism leads to an increased release of norepinephrine and serotonin.
Pregnancy and breastfeeding
Pregnancy: use only if benefit outweighs risk. Breastfeeding: discuss with your physician.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Remeron
Remeron, manufactured by Organon, is an established treatment for Major Depressive Disorder containing the active ingredient mirtazapine. The same compound is also sold under other trade names including Zispin. The medication is supplied as a tablet in strengths of 7.5mg, 15mg, and 30mg.
Remeron availability in Asia
Remeron is registered across 14 markets in the region, including Malaysia, the Philippines and Indonesia, with availability extending to Taiwan, South Korea and Japan. Generic mirtazapine, often produced in India, offers an alternative option for patients throughout Asia. For expats residing far from a medical clinic, this access is beneficial. As with all treatments for mental health, it is best used under the guidance of a medical professional.