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Sinequan
Antidepressants

Sinequan

Doxepin

Doxepin 10mg, 25mg and 75mg hard capsules, used in the management of major depression and anxiety disorder. A tricyclic acting on both amines.

Category
Antidepressants
Active ingredient
Doxepin
Route
Oral use
Form
Capsule, hard
Strengths
10 · 25 · 75mg

You will receive a quality generic equivalent, depending on stock.

Prescription rules on Sinequan vary by country.

Sinequan details

Conditions
Major Depressive Disorder · Anxiety
Therapeutic class
Tricyclic Antidepressant
Pharmacological class
Tricyclic Antidepressant (TCA)
Known off-label uses
insomnia
Contraindications
urinary retention; narrow-angle glaucoma; concurrent use of MAO inhibitors
Precautions and warnings
may cause drowsiness; caution in prostatic hypertrophy
Minor side effects
dry mouth; blurred vision; constipation; drowsiness
Moderate side effects
tachycardia; orthostatic hypotension
Dosage forms
Capsule, hard
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Originator
Pfizer
Onset Time
2–3 weeks
Duration
long-term
Storage instructions
Store at room temperature in a dry place.
Drug interactions
Alcohol; Antihistamines; MAO inhibitors
Age restrictions
Use with caution in elderly patients.
Pregnancy and breastfeeding
Pregnancy: consult a doctor. Breastfeeding: not recommended.
Serious side effects

suicidal ideation, requires immediate medical attention; cardiac arrhythmia, requires immediate medical attention

Patient summary

Doxepin 10mg, 25mg and 75mg hard capsules, used in the management of major depression and anxiety disorder. A tricyclic acting on both amines.

Mechanism of action

Doxepin acts by inhibiting the reuptake of both serotonin and norepinephrine in the central nervous system synapses, thereby increasing their concentration and improving mood.

What you will receive

Sinequan is the originator brand name, made by Pfizer. We use it here to identify the medicine only; we are not affiliated with Pfizer and do not ship the original Sinequan.

  • You receive a generic equivalent: the same active ingredient (Doxepin) at the same dose, mostly recognised Indian branded generics from vetted manufacturers.
  • The exact brand supplied depends on what is in stock at the dispatching warehouse.
  • A regulated generic matches the original ingredient for ingredient by legal standard.

Are all generics really the same? Read the honest answer.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Sinequan

Sinequan contains Doxepin, a medication for treating Major Depressive Disorder, Anxiety and Anxiety Disorder. Pfizer provides this preparation as a tablet in strengths of 10, 25 and 75mg. The formulation is intended to support those managing mental health concerns and requires use under a doctor’s care for the best outcomes.

Sinequan availability in Asia

Sinequan is registered across 13 markets including the Philippines, Indonesia and Taiwan, with wider availability in South Korea, the UAE and Singapore. Generic Doxepin, much of it made in India, is often available as a more affordable alternative to the original brand. For expats and people residing in areas with limited medical infrastructure, identifying these options supports consistent health management. Patients should ensure they use this medication under the guidance and supervision of their doctor.