Grifulvin
Designed to manage dermatophyte infections to target fungal growth in the hair, skin, and nails.
- Category
- Antifungals
- Active ingredient
- Griseofulvin
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Tablet
- Strengths
- 250mg
Grifulvin details
- Conditions
- Dermatophytosis · Tinea Capitis · Tinea Corporis · Tinea Pedis
- Alternative names
- Fulcin; Fulvicin; Fulicin; Grisovin; Likuden
- Therapeutic class
- Antifungal
- Pharmacological class
- Benzofuran
- Minor side effects
- nausea; diarrhoea; headache
- Moderate side effects
- skin rash; urticaria
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Ortho-McNeil
- Onset Time
- several days
- Duration
- several weeks
- Storage instructions
- Store at ambient temperatures in a dry environment.
- Drug interactions
- warfarin; hormonal contraceptives; alcohol
- Age restrictions
- Safe for children when dosed according to body weight by a physician.
Contraindications
hypersensitivity to griseofulvin; porphyria; severe hepatic impairment; systemic lupus erythematosus
Precautions and warnings
avoid prolonged sun and UV exposure; use caution in patients with history of liver disease; contraceptive failure risk
Serious side effects
hepatotoxicity, requires immediate medical attention; leukopenia, requires immediate medical attention; erythema multiforme, requires immediate medical attention
Patient summary
designed to manage dermatophyte infections to target fungal growth in the hair, skin, and nails.
Mechanism of action
Griseofulvin is fungistatic. It works by binding to tubulin, which interferes with microtubule function and inhibits mitosis in fungal cells. It deposits in keratin precursor cells, making the newly formed keratin resistant to fungal invasion.
Pregnancy and breastfeeding
Pregnancy: Avoid use due to potential risk to the developing foetus. Breastfeeding: Generally not recommended.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Grifulvin
Grifulvin is a brand name for Griseofulvin, an antifungal medication used to treat Dermatophytosis, Tinea Capitis and Tinea Corporis. This active ingredient is also marketed under brands including Fulcin, Fulvicin, Fulicin and Grisovin. It is supplied as a 250mg tablet, originally formulated by Ortho-McNeil for the management of persistent fungal skin and hair infections.
Buying Grifulvin online
Grifulvin is registered across 14 markets, including the Philippines, Indonesia and Taiwan, with additional availability in South Korea, Japan and the UAE. Generic Griseofulvin is often more affordable than the original brand, providing a practical option for expats living far from regular local medical supplies. As one of our most ordered antifungal treatments, it is available for prompt delivery across the region.