Ziac
Hydrochlorothiazide · Bisoprolol
Indicated for hypertension utilized to support blood pressure management.
- Category
- Heart & Blood Pressure
- Active ingredients
- Hydrochlorothiazide · Bisoprolol
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 2.5/6.25mg
Ziac details
- Condition
- Hypertension
- Alternative names
- Lodoz
- Therapeutic class
- Beta-blocker; Thiazide Diuretic
- Pharmacological class
- Cardioselective Beta-blocker
- Precautions and warnings
- monitor electrolyte levels; avoid abrupt cessation
- Minor side effects
- fatigue; dizziness; headache; cold extremities
- Moderate side effects
- bradycardia; hypokalaemia; hyperuricaemia
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Patient summary
- Indicated for hypertension utilized to support blood pressure management.
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Merck KGaA
- Onset Time
- 1–2 weeks
- Duration
- 24 hours
- Storage instructions
- Store in original packaging at room temperature.
- Drug interactions
- lithium; nsaids
- Age restrictions
- Not suitable for children.
- Pregnancy and breastfeeding
- Pregnancy: Not recommended. Breastfeeding: Not recommended.
Contraindications
asthma; severely impaired hepatic function; anuria; second or third-degree heart block
Serious side effects
heart block, requires immediate medical attention; severe electrolyte imbalance, requires immediate medical attention
Mechanism of action
Bisoprolol blocks beta-1 adrenergic receptors to reduce heart rate, while hydrochlorothiazide promotes excretion of water and electrolytes, reducing overall blood pressure.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Ziac
Ziac provides a combination of hydrochlorothiazide and bisoprolol to manage hypertension. The same active ingredients are also marketed under the brand name Lodoz. This medication is produced by Merck KGaA as a tablet in the 2.5/6.25mg strength for patients requiring consistent blood pressure support.
Buying Ziac online
Ziac is registered across 13 markets including Taiwan, South Korea and Japan, with availability also in the UAE, Singapore and Hong Kong. Because generic hydrochlorothiazide and bisoprolol, often manufactured in India, offer a more affordable route for expats, many people choose this option when far from a well stocked pharmacy. It is one of the most ordered products across the region for those managing their health.