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Ziac

Hydrochlorothiazide · Bisoprolol

Indicated for hypertension utilized to support blood pressure management.

Active ingredients
Hydrochlorothiazide · Bisoprolol
Route
Oral use
Form
Film-coated tablet
Strengths
2.5/6.25mg

You will receive a quality generic equivalent, depending on stock.

Prescription rules on Ziac vary by country.

Ziac details

Condition
Hypertension
Alternative names
Lodoz
Therapeutic class
Beta-blocker; Thiazide Diuretic
Pharmacological class
Cardioselective Beta-blocker
Precautions and warnings
monitor electrolyte levels; avoid abrupt cessation
Minor side effects
fatigue; dizziness; headache; cold extremities
Moderate side effects
bradycardia; hypokalaemia; hyperuricaemia
Dosage forms
Film-coated tablet
Administration route
Oral use
Patient summary
Indicated for hypertension utilized to support blood pressure management.
Supply category
Pharmacist only, dispensed without a prescription
Originator
Merck KGaA
Onset Time
1–2 weeks
Duration
24 hours
Storage instructions
Store in original packaging at room temperature.
Drug interactions
lithium; nsaids
Age restrictions
Not suitable for children.
Pregnancy and breastfeeding
Pregnancy: Not recommended. Breastfeeding: Not recommended.
Contraindications

asthma; severely impaired hepatic function; anuria; second or third-degree heart block

Serious side effects

heart block, requires immediate medical attention; severe electrolyte imbalance, requires immediate medical attention

Mechanism of action

Bisoprolol blocks beta-1 adrenergic receptors to reduce heart rate, while hydrochlorothiazide promotes excretion of water and electrolytes, reducing overall blood pressure.

What you will receive

Ziac is the originator brand name, made by Merck KGaA. We use it here to identify the medicine only; we are not affiliated with Merck KGaA and do not ship the original Ziac.

  • You receive a generic equivalent: the same active ingredient (Hydrochlorothiazide / Bisoprolol) at the same dose, mostly recognised Indian branded generics from vetted manufacturers.
  • The exact brand supplied depends on what is in stock at the dispatching warehouse.
  • A regulated generic matches the original ingredient for ingredient by legal standard.

Are all generics really the same? Read the honest answer.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Ziac

Ziac provides a combination of hydrochlorothiazide and bisoprolol to manage hypertension. The same active ingredients are also marketed under the brand name Lodoz. This medication is as a tablet in the 2.5/6.25mg strength for patients requiring consistent blood pressure support.

Buying Ziac online

Ziac is registered across 13 markets including Taiwan, South Korea and Japan, with availability also in the UAE, Singapore and Hong Kong. Because generic hydrochlorothiazide and bisoprolol, often manufactured in India, offer a more affordable route for expats, many people choose this option when far from a well stocked pharmacy. It is one of the most ordered products across the region for those managing their health.