Hyzaar

Losartan · Hydrochlorothiazide

Developed to mitigate hypertension to alleviate cardiovascular strain.

Active ingredients
Losartan · Hydrochlorothiazide
Supply
Pharmacy
Route
Oral use
Form
Film-coated tablet
Strengths
12.5mg

Hyzaar details

Condition
Hypertension
Alternative names
Cozaar-Comp
Therapeutic class
Angiotensin II Receptor Antagonist; Thiazide Diuretic
Pharmacological class
Sartan; Thiazide
Contraindications
anuria; pregnancy; hypersensitivity to sulfonamides
Precautions and warnings
regular blood pressure monitoring; maintain adequate hydration
Minor side effects
dizziness; fatigue
Moderate side effects
hypotension; electrolyte disturbance; back pain
Dosage forms
Film-coated tablet
Administration route
Oral use
Patient summary
developed to mitigate hypertension to alleviate cardiovascular strain.
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Merck
Onset Time
1–2 hours
Duration
24 hours
Storage instructions
Store in the original container protected from light.
Drug interactions
potassium supplements; lithium
Pregnancy and breastfeeding
Pregnancy: contraindicated. Breastfeeding: not recommended.
Serious side effects

angioedema, requires immediate medical attention; renal failure, requires immediate medical attention

Mechanism of action

it combines an angiotensin II receptor antagonist and a thiazide diuretic to inhibit the renin-angiotensin system and enhance sodium excretion.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Hyzaar

Hyzaar is a well-established medication used to manage hypertension, combining the active ingredients losartan and hydrochlorothiazide. The treatment, produced by Merck, is also available under the brand name Cozaar-comp. Many patients rely on this tablet form, which comes in a 12.5mg strength, to regulate blood pressure and support daily cardiovascular health.

Buying Hyzaar online

Hyzaar is one of the most ordered medications across the region, registered in 14 markets including the UAE, Singapore and Hong Kong. It is also widely available for patients in Thailand, Malaysia and the Philippines. Generic versions of the losartan and hydrochlorothiazide combination are often more affordable than the original brand, creating a viable path for expats and locals to maintain their health routines when they are far from home.