Esidrix

Hydrochlorothiazide

Indicated to manage fluid retention through increased sodium and water excretion in the kidneys.

Active ingredient
Hydrochlorothiazide
Supply
Pharmacy
Route
Oral use
Form
Tablet
Strengths
12.5 · 25mg

Esidrix details

Conditions
Hypertension · Oedema
Alternative names
Hydrosaluric
Therapeutic class
Thiazide Diuretic
Pharmacological class
Thiazide
Minor side effects
dizziness; fatigue; electrolyte imbalance
Moderate side effects
hypotension; hyperuricaemia; photosensitivity
Dosage forms
Tablet
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Novartis
Onset Time
1–2 hours
Duration
6–12 hours
Storage instructions
Store at room temperature in a dry place.
Drug interactions
alcohol; lithium; corticosteroids
Age restrictions
Safety in children not fully established.
Contraindications

hypersensitivity to thiazides; anuria; severe renal impairment; addison's disease

Precautions and warnings

monitor electrolyte levels regularly; may cause dehydration; report any signs of skin lesion clusters

Serious side effects

pancreatitis, requires immediate medical attention; acute renal failure, requires immediate medical attention

Patient summary

indicated to manage fluid retention through increased sodium and water excretion in the kidneys.

Mechanism of action

Esidrix works by inhibiting the reabsorption of sodium and chloride in the distal convoluted tubules of the kidney. This increases the excretion of sodium, water, and potassium, which reduces total blood volume and thereby lowers blood pressure and relieves oedema associated with congestive heart failure.

Pregnancy and breastfeeding

Pregnancy: Not recommended due to potential neonatal side effects. Breastfeeding: Avoid as it may suppress lactation.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Esidrix

Esidrix contains the active ingredient Hydrochlorothiazide, which is indicated for the management of hypertension and oedema. The same medicinal component is also marketed under the brand name Hydrosaluric. This medication is supplied as a tablet, available in strengths of 12.5mg and 25mg to suit established treatment plans.

Buying Esidrix online

Esidrix is registered across 13 markets, including Hong Kong, Thailand and Malaysia, with consistent availability throughout the Philippines, Indonesia and Taiwan. As a widely utilised medication, it is one of the most ordered treatments of its kind across the region. Hydrochlorothiazide, often sourced from high-quality manufacturers in India, remains a highly affordable alternative to original brands for expats and residents far from their regular supplier.