Aldactone
Formulated to alleviate fluid retention, indicated to support blood pressure management and target mineralocorticoid receptors.
- Category
- Heart & Blood Pressure
- Active ingredient
- Spironolactone
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 25 · 100mg
Aldactone details
- Conditions
- Hypertension · Oedema · Heart Failure · Hyperaldosteronism
- Therapeutic class
- Diuretic
- Pharmacological class
- Aldosterone Antagonist
- Known off-label uses
- hirsutism
- Contraindications
- hypersensitivity to spironolactone; Addison's disease; hyperkalaemia; anuria
- Minor side effects
- headache; gastrointestinal disturbances; drowsiness
- Moderate side effects
- gynaecomastia; menstrual irregularities; hyponatraemia
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Pfizer
- Onset Time
- 2–4 days
- Duration
- 2–3 days
- Storage instructions
- Store below 25°C, protected from light.
- Drug interactions
- potassium-sparing diuretics; ACE inhibitors
- Age restrictions
- Use with caution in elderly patients.
- Pregnancy and breastfeeding
- Use only if benefit outweighs risk.
Precautions and warnings
regular blood monitoring of potassium levels required; avoid excessive salt intake; may affect urination frequency
Serious side effects
severe hyperkalaemia, requires immediate medical attention; arrhythmia, requires immediate medical attention
Patient summary
Formulated to alleviate fluid retention, indicated to support blood pressure management and target mineralocorticoid receptors.
Mechanism of action
It serves as a competitive antagonist of aldosterone. By blocking the effects of aldosterone in the distal renal tubules, it increases sodium and water excretion while retaining potassium, which helps reduce excess fluid and pressure.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Aldactone
Aldactone is the primary brand name for spironolactone, a well-established medication used in the management of hypertension, oedema and heart failure. Supplied as a tablet by Pfizer, options include strengths of 25mg and 100mg. Many patients requiring this type of therapy view the drug as a foundational component of their ongoing treatment.
Buying Aldactone online
Aldactone is currently registered across 14 markets, including South Korea, Japan and the UAE, with consistent availability throughout Singapore, Hong Kong and Thailand. While the original brand remains a preferred choice for many, generic versions containing spironolactone are often produced in India to provide a significantly more affordable option. This makes the treatment accessible for expats and those living in regions where local medicine supply may be restricted.