Zestril
Designed to relieve hypertension and indicated to support cardiovascular health in patients.
- Category
- Heart & Blood Pressure
- Active ingredient
- Lisinopril
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Tablet
- Strengths
- 2.5 · 5 · 10mg
Zestril details
- Conditions
- Hypertension · Heart Failure · Myocardial Infarction
- Alternative names
- Lopace; Prinivil
- Therapeutic class
- ACE Inhibitor
- Pharmacological class
- ACE Inhibitor
- Known off-label uses
- diabetic nephropathy
- Contraindications
- history of angioedema; pregnancy; renal artery stenosis
- Minor side effects
- dizziness; headache; fatigue; dry cough
- Moderate side effects
- hypotension; diarrhoea; rash; nausea
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- AstraZeneca
- Onset Time
- 1 hour
- Duration
- 24 hours
- Storage instructions
- Store below 25°C.
- Drug interactions
- Potassium-sparing diuretics; Potassium supplements; NSAIDs
- Age restrictions
- Use with caution in children over six years.
- Pregnancy and breastfeeding
- Pregnancy: Discontinue immediately. Breastfeeding: Not recommended.
Precautions and warnings
monitor renal function; check blood pressure regularly; may cause lightheadedness on standing
Serious side effects
angioedema, requires immediate medical attention; hyperkalaemia, requires immediate medical attention; jaundice, requires immediate medical attention
Patient summary
Designed to relieve hypertension and indicated to support cardiovascular health in patients.
Mechanism of action
This agent inhibits the angiotensin-converting enzyme, which prevents the conversion of angiotensin I to the potent vasoconstrictor angiotensin II. This leads to widened blood vessels, reduced workload on the heart, and lower systemic blood pressure.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Zestril
Zestril is the original brand name for lisinopril, used to manage hypertension, heart failure and myocardial infarction. This active ingredient is also available under brand names like Lopace and Prinivil. The treatment is produced by AstraZeneca and supplied as a tablet in strengths of 2.5, 5, and 10mg.
Buying Zestril online
Zestril is one of the most ordered cardiovascular medications across the region, currently registered in 14 markets including the Philippines, Indonesia and Taiwan, with availability also in South Korea, Japan and the UAE. Generic lisinopril, often produced in India, offers a far more affordable alternative to the original brand. This ensures reliable access for expats and residents throughout Asia who require consistent, cost-effective treatment regimens.