Metaglip

Glipizide · Metformin

Formulated to manage type 2 diabetes mellitus, this combined therapy is utilized to support blood glucose control and to mitigate glycemic fluctuations.

Active ingredients
Glipizide · Metformin
Supply
Pharmacy
Route
Oral use
Form
Tablet
Strengths
2.5/500 · 5/500mg

Metaglip details

Alternative names
Glucovance
Therapeutic class
Biguanide; Sulfonylurea
Pharmacological class
Biguanide; Sulfonylurea
Precautions and warnings
monitor blood glucose levels; risk of lactic acidosis; monitor for hypoglycaemia
Minor side effects
nausea; diarrhoea; abdominal discomfort
Moderate side effects
hypoglycaemia; dizziness; weight gain
Dosage forms
Tablet
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Bristol-Myers Squibb
Onset Time
1–2 hours
Duration
12–24 hours
Storage instructions
Store at room temperature.
Drug interactions
alcohol; cimetidine; diuretics; corticosteroids
Age restrictions
Not for use in children.
Pregnancy and breastfeeding
Pregnancy: Insulin is preferred. Breastfeeding: Not recommended.
Contraindications

type 1 diabetes; diabetic ketoacidosis; severe renal impairment; severe hepatic impairment

Serious side effects

lactic acidosis, requires immediate medical attention; anaphylaxis, requires immediate medical attention

Patient summary

Formulated to manage type 2 diabetes mellitus, this combined therapy is utilized to support blood glucose control and to mitigate glycemic fluctuations.

Mechanism of action

Metformin reduces hepatic glucose production and increases insulin sensitivity, while glipizide stimulates pancreatic insulin secretion, providing a dual approach to glycemic management.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Metaglip

Metaglip contains glipizide and metformin, which are used together for the management of Type 2 Diabetes Mellitus. This medication combination is also sold under the brand name Glucovance. Manufactured by Bristol-Myers Squibb, it is supplied as a tablet in strengths of 2.5/500mg and 5/500mg.

Buying Metaglip online

Metaglip is registered across 13 markets, including Malaysia, the Philippines and Indonesia, with availability in Taiwan, South Korea and Japan. Since generic glipizide and metformin, often produced in India, offers a more affordable price point than the original brand, many expats and those in remote areas rely on these consistent supplies. It remains one of our frequently ordered products for glucose management, available for delivery across the region.