Kombiglyze Xr

Saxagliptin · Metformin

Utilized to manage type 2 diabetes to support glycaemic control.

Active ingredients
Saxagliptin · Metformin
Supply
Pharmacy
Route
Oral use
Form
Prolonged-release tablet
Strengths
5/500 · 5/1000mg

Kombiglyze Xr details

Alternative names
Kombiglyze
Therapeutic class
Dipeptidyl peptidase-4 (DPP-4) inhibitor and biguanide combination
Pharmacological class
Biguanide; DPP-4 inhibitor
Contraindications
diabetic ketoacidosis; renal impairment; hypersensitivity
Minor side effects
nausea; diarrhoea; gastrointestinal distress
Moderate side effects
urinary tract infection; headache
Dosage forms
Prolonged-release tablet
Administration route
Oral use
Patient summary
Utilized to manage type 2 diabetes to support glycaemic control.
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
AstraZeneca
Onset Time
1–2 weeks
Duration
Ongoing
Storage instructions
Store below 25°C.
Drug interactions
Alcohol; Cimetidine
Age restrictions
Not for children.
Pregnancy and breastfeeding
Pregnancy: Use is not recommended. Breastfeeding: Not recommended.
Precautions and warnings

risk of lactic acidosis; monitor renal function; watch for symptoms of pancreatitis

Serious side effects

lactic acidosis, requires immediate medical attention; pancreatitis, requires immediate medical attention

Mechanism of action

Combines a DPP-4 inhibitor to increase insulin release and a biguanide to decrease hepatic glucose production and improve insulin sensitivity.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Kombiglyze Xr

Kombiglyze Xr combines Saxagliptin and Metformin to assist with the management of Type 2 Diabetes Mellitus. The same fixed-dose combination is also supplied as Kombiglyze. This medication from AstraZeneca is provided in extended-release tablet form, with available strengths ranging between 5/500 and 5/1000mg for specific requirements.

Buying Kombiglyze Xr online

Kombiglyze Xr is registered across 13 markets including Hong Kong, Thailand and Malaysia, with steady availability throughout the Philippines, Indonesia and Taiwan. Generic versions containing Saxagliptin and Metformin are often significantly more affordable than the original brand, offering a practical solution for expats and those living in areas without consistent local supply. Kombiglyze Xr is one of the most frequently ordered treatments across the region, with reliable delivery to your residence in these locations.