Hygroton

Chlorthalidone

Utilized to mitigate excess fluid retention and intended to support the management of essential hypertension.

Active ingredient
Chlorthalidone
Supply
Pharmacy
Route
Oral use
Form
Tablet
Strengths
6.25 · 12.5mg

Hygroton details

Conditions
Hypertension · Oedema
Therapeutic class
Thiazide-like Diuretic
Pharmacological class
Thiazide-like Diuretic
Known off-label uses
nephrogenic diabetes insipidus
Contraindications
anuria; severe renal insufficiency; hypersensitivity to sulfonamides
Minor side effects
dizziness; fatigue; muscle cramps
Moderate side effects
hypokalaemia; hyperuricaemia; hyponatraemia
Dosage forms
Tablet
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Sanofi
Onset Time
2 hours
Duration
24–72 hours
Storage instructions
Store at controlled room temperature.
Drug interactions
lithium; nsaids
Precautions and warnings

monitor potassium levels; regular blood sugar checks; caution in patients with gout

Serious side effects

severe electrolyte imbalance, requires immediate medical attention; acute pancreatitis, requires immediate medical attention

Patient summary

utilized to mitigate excess fluid retention and intended to support the management of essential hypertension.

Mechanism of action

Chlorthalidone acts on the distal convoluted tubule in the kidney to inhibit sodium and chloride reabsorption, increasing water excretion and lowering blood pressure while maintaining efficacy over 24 hours.

Pregnancy and breastfeeding

Pregnancy: Monitor closely if used during pregnancy. Breastfeeding: Chlorthalidone passes into breast milk; use with caution.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Hygroton

Hygroton is a brand of chlorthalidone, a diuretic used primarily for managing hypertension and oedema. Produced by Sanofi, this medication is supplied as a tablet in strengths of 6.25mg and 12.5mg. It assists the body in managing fluid levels and salt excretion, supporting the long-term control of blood pressure and associated systemic fluid retention.

Buying Hygroton online

Hygroton is registered across 14 markets, including Indonesia, Taiwan and South Korea, with availability also in Japan, the UAE and Singapore. As one of the more frequently ordered treatments across the region, generic chlorthalidone options often offer an affordable alternative to the original brand for expats and local residents. These tablets can be ordered online with delivery provided across our covered Asian and Middle Eastern destinations.