Zocor
Indicated to support the reduction of cholesterol levels, formulated to mitigate cardiovascular risk by inhibiting a key enzyme in cholesterol synthesis.
- Category
- Cholesterol Management
- Active ingredient
- Simvastatin
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 5 · 10 · 20 · 40mg
Zocor details
- Conditions
- Hypercholesterolaemia · Coronary Heart Disease
- Therapeutic class
- HMG-CoA Reductase Inhibitor
- Pharmacological class
- Statin
- Contraindications
- hypersensitivity to simvastatin; active liver disease; pregnancy; breastfeeding
- Minor side effects
- headache; constipation; nausea
- Moderate side effects
- myalgia; abdominal pain; dizziness
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- MSD
- Onset Time
- 2 weeks
- Duration
- 4–6 weeks
- Storage instructions
- Store below 30°C.
- Drug interactions
- grapefruit juice; amiodarone; verapamil
- Age restrictions
- Typically for adults.
- Pregnancy and breastfeeding
- Pregnancy: contra-indicated. Breastfeeding: contra-indicated.
Precautions and warnings
report unexplained muscle pain immediately; regular liver function monitoring advised
Serious side effects
rhabdomyolysis, requires immediate medical attention; myopathy, requires immediate medical attention; hepatitis, requires immediate medical attention
Patient summary
Indicated to support the reduction of cholesterol levels, formulated to mitigate cardiovascular risk by inhibiting a key enzyme in cholesterol synthesis.
Mechanism of action
Simvastatin is an HMG-CoA reductase inhibitor. It competitively inhibits the enzyme HMG-CoA reductase, which is responsible for the conversion of HMG-CoA to mevalonate, the rate-limiting step in cholesterol biosynthesis in the liver.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Zocor
Zocor is the original branded version of simvastatin, a medication used to manage hypercholesterolaemia and reduce the risk of coronary heart disease. Produced by MSD, this medicine is supplied as a tablet in strengths of 5, 10, 20, and 40mg. It functions as a statin to help lower unhealthy cholesterol levels in the blood.
Buying Zocor online
Zocor is registered across 14 markets including Singapore, Hong Kong and Thailand, with availability also in Malaysia, the Philippines and Indonesia. Providing consistent access to heart health maintenance is important for expats and residents living across the region. As one of the most frequently ordered brands on our site, it remains a popular choice for those seeking to continue their established management routine when distant from their home country care.