Questran

Colestyramine

Indicated for hypercholesterolaemia, utilized to target bile acids in the gut to alleviate elevated blood cholesterol and support lipid management.

Active ingredient
Colestyramine
Supply
Pharmacy
Route
Oral use
Form
Powder for oral suspension
Strengths
4g

Questran details

Therapeutic class
Bile Acid Sequestrant
Pharmacological class
Ion Exchange Resin
Contraindications
complete biliary obstruction
Minor side effects
constipation; nausea
Moderate side effects
abdominal bloating; flatulence; fat malabsorption
Serious side effects
intestinal obstruction, requires immediate medical attention
Dosage forms
Powder for oral suspension
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Bristol-Myers Squibb
Onset Time
1–2 weeks
Duration
24 hours
Storage instructions
Store in a tightly closed container at room temperature.
Drug interactions
warfarin; fat-soluble vitamins; thiazide diuretics
Age restrictions
Use with caution in children.
Pregnancy and breastfeeding
Pregnancy: Use only if necessary. Breastfeeding: Generally considered safe.
Precautions and warnings

take other medications at least one hour before or four hours after; maintain adequate fluid intake

Patient summary

Indicated for hypercholesterolaemia, utilized to target bile acids in the gut to alleviate elevated blood cholesterol and support lipid management.

Mechanism of action

Cholestyramine is a bile acid sequestrant. It binds to bile acids in the intestine, forming an insoluble complex that is excreted in faeces. This forces the liver to use cholesterol to produce more bile acids, lowering overall blood cholesterol levels.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Questran

Questran contains Colestyramine, a bile acid sequestrant used for the management of hypercholesterolaemia and pruritus. Manufactured by Bristol-Myers Squibb, this medicine is supplied in a sachet form at a strength of 4g. It functions by binding bile acids in the intestine, which helps to lower cholesterol levels and ease specific itching symptoms associated with bile flow issues.

Buying Questran online

Questran is registered across 14 markets, including Indonesia, Taiwan and South Korea, with availability also in Japan, the UAE and Singapore. For expats, finding consistent access to specialised medicine can be challenging. Generic versions of Colestyramine, often manufactured in India, are frequently far more affordable than the original brand. This treatment remains one of the most ordered options online for those requiring convenient delivery across the region, allowing patients to maintain their long-term health routine without local disruption.