Nexletol
Utilized to target hypercholesterolaemia to mitigate cardiovascular risk.
- Categories
- Heart & Blood Pressure · Cholesterol Management
- Active ingredient
- Bempedoic Acid
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 180mg
Nexletol details
- Conditions
- Primary Hypercholesterolaemia · Mixed Dyslipidaemia
- Alternative names
- Nilemdo
- Therapeutic class
- Adenosine triphosphate-citrate lyase inhibitor
- Pharmacological class
- Lipid-lowering agent
- Contraindications
- hypersensitivity to bempedoic acid; pregnancy; breastfeeding
- Minor side effects
- hyperuricaemia; muscle spasms; back pain; abdominal pain
- Moderate side effects
- gout; anaemia; increased liver enzymes
- Serious side effects
- tendon rupture, requires immediate medical attention
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Patient summary
- Utilized to target hypercholesterolaemia to mitigate cardiovascular risk.
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Daiichi Sankyo
- Onset Time
- 2–4 weeks
- Duration
- Ongoing
- Storage instructions
- Store below 30°C.
- Drug interactions
- Simvastatin; Pravastatin
- Age restrictions
- Not for use in children.
- Pregnancy and breastfeeding
- Pregnancy: Contraindicated. Breastfeeding: Do not use during breastfeeding.
Precautions and warnings
monitor uric acid levels; caution in patients with history of gout; monitor for tendon rupture
Mechanism of action
Bempedoic acid inhibits ATP-citrate lyase, an enzyme involved in cholesterol biosynthesis in the liver, resulting in reduced LDL-cholesterol levels in the blood.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Nexletol
Nexletol contains bempedoic acid, a treatment used to assist in the management of primary hypercholesterolaemia and mixed dyslipidaemia. The same active ingredient is also sold as Nilemdo. This medication is supplied as a 180mg tablet, manufactured by Daiichi Sankyo for patients seeking to regulate their lipid levels effectively.
Buying Nexletol online
Nexletol is registered across 14 markets including Thailand, Malaysia and the Philippines, with availability also in Indonesia, Taiwan and South Korea. As a specialised cholesterol management option, it is often ordered online by expats and residents across the region who require consistent access to their medication. By sourcing directly, many find a more reliable supply chain compared to relying on a local pharmacy, particularly when staying in more remote locations.