Vfend
Developed to target serious fungal infections, this medication is indicated to address invasive aspergillosis and is utilized in systemic treatment protocols.
- Category
- Antifungals
- Active ingredient
- Voriconazole
- Supply
- Pharmacy
- Route
- Oral use
- Form
- Film-coated tablet
- Strengths
- 200mg
Vfend details
- Conditions
- Invasive Aspergillosis · Candidemia · Oesophageal Candidiasis
- Therapeutic class
- Triazole Antifungal
- Pharmacological class
- Antifungal
- Precautions and warnings
- avoid prolonged sun exposure; monitor liver function; monitor visual function
- Minor side effects
- visual disturbances; nausea; vomiting; rash
- Moderate side effects
- elevated liver enzymes; peripheral oedema; headache
- Dosage forms
- Film-coated tablet
- Administration route
- Oral use
- Supply category
- Pharmacist only, dispensed without a prescription
- Manufacturer
- Pfizer
- Onset Time
- 1–2 hours
- Duration
- 12 hours
- Storage instructions
- Store at room temperature.
- Drug interactions
- rifampicin; carbamazepine; pimozide; quinidine
- Age restrictions
- Use with caution in paediatric patients.
Contraindications
hypersensitivity to voriconazole; concurrent use of rifampicin; concurrent use of carbamazepine
Serious side effects
hepatotoxicity, requires immediate medical attention; photosensitivity, requires immediate medical attention; qt prolongation, requires immediate medical attention
Patient summary
Developed to target serious fungal infections, this medication is indicated to address invasive aspergillosis and is utilized in systemic treatment protocols.
Mechanism of action
Voriconazole inhibits fungal cytochrome P450-dependent 14-alpha-sterol demethylase, which is vital for fungal ergosterol biosynthesis, effectively disrupting fungal cell membrane formation.
Pregnancy and breastfeeding
Pregnancy: Use is not recommended unless clearly necessary. Breastfeeding: Discontinue breastfeeding during treatment.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Vfend
Vfend contains voriconazole, an antifungal agent used to treat severe fungal infections like invasive aspergillosis, candidemia and oesophageal candidiasis. Manufactured by Pfizer, this treatment comes as 200mg tablets. Voriconazole acts by inhibiting the growth of fungi, assisting in the management of these infections when under the supervision of a healthcare provider.
Buying Vfend online
Vfend is registered across 14 markets including Indonesia, Taiwan and South Korea, with availability also in Japan, the UAE and Singapore. Securing reliable access to specific antifungal treatments can be difficult for expats or those travelling across the region. Vfend remains a commonly ordered option for those in need, offering direct delivery across these registered markets to ensure consistent support.