Oesophageal Candidiasis

Oesophageal candidiasis is a Candida yeast infection of the oesophagus (the tube connecting the throat to the stomach). Unlike oral thrush, which is visible in the mouth, this infection sits deeper and is most common in people whose immune defences are significantly reduced, such as those living with HIV, undergoing chemotherapy, or taking high-dose corticosteroids.

Medicine used to treat Oesophageal Candidiasis

Vfend

Voriconazole

200mg

Developed to target serious fungal infections, this medication is indicated to address invasive aspergillosis and is utilized in systemic treatment protocols.

From $31.20 / tablet View

Why the oesophagus, and who is at risk

Candida normally lives on skin and mucosal surfaces without causing harm. When the immune system is compromised, the yeast can overgrow and penetrate the oesophageal lining. The hallmark symptom is painful or difficult swallowing (odynophagia or dysphagia), sometimes with a sensation that food is sticking. Chest discomfort behind the breastbone is also common. Nausea and reduced appetite can follow if the infection is extensive.

People in South and Southeast Asia who are managing HIV or receiving cancer treatment face the same risks as anywhere in the world. Diagnosis usually requires endoscopy to confirm the white plaques characteristic of the infection.

Antifungal treatment

Systemic antifungals are needed because topical agents cannot reach the oesophagus reliably. Voriconazole is one option used when first-line treatment has not worked or when the infecting strain is resistant. Seek prompt medical assessment if swallowing becomes very painful or you are unable to keep fluids down, as dehydration can develop quickly.