Sporanox

Itraconazole

This medication is formulated to help manage severe fungal infections and intended to relieve symptoms associated with systemic candidiasis or aspergillosis.

Category
Antifungals
Active ingredient
Itraconazole
Supply
Pharmacy
Route
Oral use
Form
Capsule, hard
Strengths
100mg

Sporanox details

Therapeutic class
Antifungal
Pharmacological class
Triazole
Precautions and warnings
monitor hepatic function; observe for signs of heart failure
Minor side effects
nausea; abdominal discomfort; headache
Moderate side effects
oedema; hypertension; rash
Dosage forms
Capsule, hard
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Janssen-Cilag
Onset Time
1–2 weeks
Duration
2–6 months
Storage instructions
Store at room temperature below 25°C.
Drug interactions
Statins; Midazolam; Digoxin; Warfarin
Age restrictions
Use with caution in elderly patients.
Pregnancy and breastfeeding
Pregnancy: avoid unless strictly necessary. Breastfeeding: not advised.
Contraindications

hypersensitivity to triazoles; heart failure; ventricular dysfunction; concurrent use of certain cardiac medications

Serious side effects

congestive heart failure, requires immediate medical attention; hepatotoxicity, requires immediate medical attention

Patient summary

This medication is formulated to help manage severe fungal infections and intended to relieve symptoms associated with systemic candidiasis or aspergillosis.

Mechanism of action

Itraconazole is a potent inhibitor of fungal cytochrome P450-dependent enzymes. This inhibits the synthesis of ergosterol, which is essential for fungal cell membrane integrity, resulting in the inhibition of fungal cell growth.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Sporanox

Sporanox is a standard antifungal treatment containing itraconazole, used for treating conditions such as candidiasis, histoplasmosis and aspergillosis. Developed by Janssen-Cilag, this medication is supplied as a 100mg tablet. It serves as an established option for patients requiring consistent support in managing their fungal health and recovery.

Buying Sporanox online

Sporanox is registered across 14 markets globally, including Thailand, Malaysia and the Philippines, with further availability in Indonesia, Taiwan and South Korea. Many patients across the region order itraconazole online to secure consistent supplies that are often more affordable than buying branded stocks in a traditional store. This access helps expats and individuals far from city centres secure their required medication without difficulty.