Serophene

Clomifene

Developed to support fertility in women and indicated to target the endocrine system for improved ovulatory function.

Active ingredient
Clomifene
Supply
Rx
Route
Oral use
Form
Tablet
Strengths
25 · 50 · 100mg

Serophene details

Alternative names
Clomid
Therapeutic class
Selective oestrogen Receptor Modulator (SERM)
Pharmacological class
SERM
Known off-label uses
hypogonadism
Contraindications
pregnancy; hepatic disease; abnormal uterine bleeding; ovarian cysts
Minor side effects
hot flushes; nausea; bloating; headache
Moderate side effects
abdominal discomfort; breast tenderness; vision disturbances
Serious side effects
ovarian hyperstimulation syndrome, requires immediate medical attention
Dosage forms
Tablet
Administration route
Oral use
Supply category
Prescription only (specially controlled medicine)
Manufacturer
Sanofi
Onset Time
5–10 days post-initiation
Duration
cycle-dependent
Storage instructions
Store in a light-resistant container.
Age restrictions
Pre-menopausal adults.
Pregnancy and breastfeeding
Do not use if pregnant.
Precautions and warnings

monitor for ovarian enlargement; multiple pregnancy risk; may affect visual acuity

Patient summary

developed to support fertility in women and indicated to target the endocrine system for improved ovulatory function.

Mechanism of action

Clomiphene acts as a selective oestrogen receptor modulator. It binds to oestrogen receptors in the hypothalamus, blocking negative feedback and stimulating the release of gonadotropins to induce ovulation.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Serophene

Serophene is a brand of clomifene, a widely used treatment for female infertility, specifically anovulation and anovulatory infertility. The same active ingredient is also sold as Clomid, supplied as a tablet in strengths of 25, 50, and 100mg. This medication, produced by Sanofi, remains a standard approach for addressing these specific fertility concerns.

Serophene availability in Asia

Serophene is registered across 14 markets including the UAE, Singapore, and Hong Kong, with availability also in Thailand, Malaysia, and the Philippines. While access to such medications can vary for expats living far from a major medical hub, the generic clomifene, often produced in India, frequently presents an accessible and affordable alternative to the original Sanofi brand. This treatment should only be used under the supervision and guidance of a medical professional.