Anovulation
Anovulation occurs when the ovaries fail to release an egg during a menstrual cycle. It is one of the most common underlying causes of irregular or absent periods and accounts for a significant proportion of female infertility cases. Many women experience occasional anovulatory cycles without noticing; persistent anovulation is what typically prompts investigation.
Medicine used to treat Anovulation
Why ovulation stops
The most frequent driver is a hormonal imbalance that disrupts the signals between the brain and the ovaries. Polycystic ovary syndrome (PCOS) is the leading cause and is particularly prevalent across South and Southeast Asia, where dietary patterns and genetic predisposition raise its incidence. Other contributors include thyroid dysfunction, elevated prolactin, significant weight changes, extreme exercise, and chronic stress.
Restoring ovulation
When lifestyle factors are involved, addressing body weight and reducing physical or psychological stress often restores normal cycles. Where medical treatment is needed, ovulation induction is the standard approach. Clomifene works by blocking oestrogen receptors in the hypothalamus, prompting the body to release more follicle-stimulating hormone and trigger egg development. It sits within the broader women’s health category of treatments aimed at correcting hormonal imbalances. Persistent or unexplained anovulation warrants investigation by a gynaecologist or reproductive endocrinologist.