Duphaston

Dydrogesterone

Duphaston is developed to target progesterone deficiency and intended to support women managing menstrual health conditions.

Active ingredient
Dydrogesterone
Supply
Pharmacy
Route
Oral use
Form
Tablet
Strengths
10mg

Duphaston details

Therapeutic class
Progestogen
Pharmacological class
Progestogen
Precautions and warnings
exclude tumour before diagnosis; monitor patients with history of depression
Minor side effects
headache; nausea; menstrual irregularities
Moderate side effects
breast pain; mood swings; migraine
Dosage forms
Tablet
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Abbott
Onset Time
2–4 weeks
Duration
8–12 hours
Storage instructions
Store in original packaging at stable temperature.
Drug interactions
Ritonavir; Nelfinavir; Phenobarbital
Age restrictions
Adults.
Contraindications

vaginal bleeding of unknown cause; severe hepatic impairment; known hypersensitivity to dydrogesterone

Serious side effects

haemolytic anaemia, requires immediate medical attention; hepatic dysfunction, requires immediate medical attention

Patient summary

Duphaston is developed to target progesterone deficiency and intended to support women managing menstrual health conditions.

Mechanism of action

Dydrogesterone is an orally active progestogen that mimics the effect of endogenous progesterone on the endometrium, enabling the transformation of the endometrium from a proliferative to a secretory phase without inhibiting ovulation.

Pregnancy and breastfeeding

Pregnancy: No evidence of harm in limited studies. Breastfeeding: Avoid unless specified by a consultant.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Duphaston

Duphaston contains dydrogesterone, a synthetic progestogen used in the treatment of endometriosis, dysmenorrhea and infertility. Produced by Abbott, the medication aids in hormonal regulation for reproductive health concerns. Duphaston is supplied as a 10mg tablet, offering a consistent and convenient dosage form for patients who require reliable hormonal therapy.

Buying Duphaston online

Duphaston is registered across 13 markets, including the UAE, Singapore and Hong Kong, with availability also in Thailand, Malaysia and the Philippines. While generic dydrogesterone, much of which is manufactured in India, is often available at a lower cost, many patients prefer the reliability of the original Abbott brand. For expats and individuals living far from a well-stocked pharmacy, ordering this medication online facilitates consistent access, making it one of the most ordered treatments across the region.