Cycrin

Medroxyprogesterone

This medicine is utilized to manage hormonal conditions like endometriosis and is indicated to support the regulation of the menstrual cycle in women.

Active ingredient
Medroxyprogesterone
Supply
Pharmacy
Route
Oral use
Form
Tablet
Strengths
5 · 10mg

Cycrin details

Alternative names
Provera
Therapeutic class
Progestogen
Pharmacological class
Progesterone
Minor side effects
headache; nausea; dizziness
Moderate side effects
weight gain; breast tenderness; insomnia
Dosage forms
Tablet
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Pfizer
Onset Time
1–3 hours
Duration
24 hours
Storage instructions
Store at room temperature, away from moisture and direct light.
Drug interactions
aminoglutethimide
Age restrictions
Not recommended for paediatric patients.
Contraindications

hypersensitivity to medroxyprogesterone; undiagnosed vaginal bleeding; severe hepatic impairment; pregnancy

Precautions and warnings

risk of venous thromboembolism; use with caution in patients with history of depression; may cause irregular bleeding patterns; monitor hepatic function

Serious side effects

anaphylaxis, requires immediate medical attention; venous thromboembolism, requires immediate medical attention

Patient summary

This medicine is utilized to manage hormonal conditions like endometriosis and is indicated to support the regulation of the menstrual cycle in women.

Mechanism of action

Medroxyprogesterone is a synthetic progestogen that acts on the endometrium, transforming proliferative endometrium into secretory endometrium. It effectively inhibits the production of pituitary gonadotropins, which prevents follicular maturation and ovulation, thereby supporting management of specific reproductive healthcare needs.

Pregnancy and breastfeeding

Pregnancy: Do not use during pregnancy. Breastfeeding: Use with caution as it may be excreted in breast milk.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Cycrin

Cycrin is a medication containing medroxyprogesterone, a synthetic progestin used in the management of secondary amenorrhea, endometriosis and dysfunctional uterine bleeding. This medication is also widely marketed under the brand name Provera. It is supplied as a tablet in strengths of 5mg and 10mg, manufactured by Pfizer.

Buying Cycrin online

Cycrin is registered across 13 markets, including Malaysia, the Philippines and Indonesia, with broad availability across Taiwan, South Korea and Japan. As one of the more ordered options for menstrual health in the region, generic medroxyprogesterone is often more affordable than original brand variants. This allows expats and residents in areas where local stock fluctuates to secure their required supply online with reliable delivery across these markets.