Arimidex

Anastrozole

Arimidex is developed to target hormone-dependent breast cancer and is formulated to alleviate tumour progression.

Active ingredient
Anastrozole
Supply
Rx
Route
Oral use
Form
Film-coated tablet
Strengths
1mg

Arimidex details

Condition
Breast Cancer
Therapeutic class
Aromatase Inhibitor
Pharmacological class
Aromatase Inhibitor
Known off-label uses
infertility
Contraindications
hypersensitivity to anastrozole; pre-menopausal women; pregnancy; breastfeeding
Minor side effects
hot flushes; asthenia; arthralgia; headache
Moderate side effects
vaginal dryness; hair thinning; nausea; rash
Dosage forms
Film-coated tablet
Administration route
Oral use
Supply category
Prescription only (specially controlled medicine)
Manufacturer
AstraZeneca
Onset Time
2–4 weeks
Duration
24 hours
Storage instructions
Store at room temperature below 30°C.
Drug interactions
Oestrogen containing therapies; Tamoxifen
Age restrictions
Indicated strictly for post-menopausal women.
Pregnancy and breastfeeding
Pregnancy: Contraindicated. Breastfeeding: Contraindicated.
Precautions and warnings

assess bone mineral density regularly; monitor lipid profile; use with caution in moderate to severe hepatic impairment

Serious side effects

osteoporosis, requires immediate medical attention; bone fractures, requires immediate medical attention; severe skin reactions, requires immediate medical attention

Patient summary

Arimidex is developed to target hormone-dependent breast cancer and is formulated to alleviate tumour progression.

Mechanism of action

This medicine acts as a potent and selective non-steroidal aromatase inhibitor. It lowers circulating oestrogen levels in post-menopausal women by blocking the enzyme responsible for the peripheral conversion of androgens into oestrogens, thereby limiting the growth of hormone-sensitive tumours.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Arimidex

Arimidex is the primary brand name for anastrozole, a medication used in the treatment of breast cancer. Manufactured by AstraZeneca, this therapy is supplied as a 1mg tablet. By reducing the concentration of the hormone oestrogen, it supports specific hormonal management protocols in patients diagnosed with this condition.

Arimidex availability in Asia

Arimidex is registered across 14 markets including Japan, the UAE and Singapore, with availability also in Hong Kong, Thailand and Malaysia. Generic anastrozole, much of it made in India, is far more affordable than the original brand, providing an important access point for expats living in regions with limited stock. This medication is intended for use under a doctor’s care to ensure the correct maintenance of hormone levels.