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Breast Cancer

Breast cancer starts when cells in the breast grow out of control. It is the most common cancer in women. Many cases are now caught early through screening, and outcomes are strong when treatment starts soon after diagnosis. Men can develop it too, though far less often.

Femara

Letrozole

2.5mg

Letrozole at a single 2.5mg film-coated strength, listed for breast cancer. Blocking aromatase stops androgens being converted into oestrogen.

From$0.51/ tabletView

Arimidex

Anastrozole

1mg

Anastrozole 1mg film-coated tablets, used in the management of breast cancer. A non-steroidal aromatase inhibitor that lowers circulating oestrogen.

From$2.34/ tabletView

Armotraz

Anastrozole

1mg

Anastrozole 1mg film-coated tablets for breast cancer, including adjuvant therapy. A selective aromatase inhibitor that halts androgen conversion to oestrogen.

From$3.11/ tabletView

Nolvadex

Tamoxifen

10 · 20mg

Tamoxifen 10mg and 20mg tablets, used in the management of oestrogen receptor positive breast cancer. A SERM that occupies the receptor in breast tissue.

From$0.32/ tabletView

Capnat

Capecitabine

500mg

Capecitabine 500mg film-coated tablets, used in the management of colorectal, breast and gastric cancer. A prodrug converted to fluorouracil in the body.

From$2.98/ tabletView

Aromasin

Exemestane

25mg

Exemestane 25mg tablets, used in the management of breast cancer. A steroidal aromatase inactivator, which shuts the enzyme down rather than blocking it.

From$4.73/ tabletView

Afinitor

Everolimus

5 · 10mg

Everolimus 5mg and 10mg tablets, used in the management of renal cell carcinoma, breast cancer and neuroendocrine tumours. An mTOR kinase inhibitor.

From$34.00/ tabletView

Key points

  • A new lump is the classic sign, but changes in shape, skin dimpling, an inverted nipple or unusual discharge are also worth checking.
  • Hormone-blocking medicines such as tamoxifen or the aromatase inhibitors are a treatment mainstay, since many cases are hormone-driven.
  • Capecitabine, an oral chemotherapy, is one option chosen once the cancer has spread beyond the breast.
  • Growing older, a family history of the disease, and specific inherited gene mutations all push up the risk, alongside weight and alcohol.

Spotting breast cancer early

The classic sign is a new lump in the breast or armpit, but the picture is wider than that. Watch for a change in breast size or shape, dimpling or puckering of the skin, a nipple that turns inward, discharge that is not milk, or a patch of skin that looks red, scaly or thickened. Most lumps turn out to be harmless, yet any change that lasts more than a couple of weeks is worth getting checked. Knowing how your breasts normally look and feel makes a new change easier to notice between screening visits.

How breast cancer is treated

Treatment is tailored to the type and stage of the cancer, and usually combines surgery with one or more drug therapies. Many breast cancers are hormone-driven, so hormone-blocking medicines are a mainstay: tamoxifen for many premenopausal women, and aromatase inhibitors such as anastrozole, letrozole and exemestane after menopause. Everolimus is added in some advanced hormone-positive cases, while capecitabine is an oral chemotherapy used when the disease has spread. You can see the full range on our oncology support page. These treatments work best alongside an oncology team that monitors response and manages side effects.

Risk and what helps

Age, family history and inherited gene changes raise the odds, and so do factors you can influence, including weight, alcohol and physical inactivity. Staying active, keeping a healthy weight and limiting alcohol all lower risk modestly. Equally important is turning up for screening when invited and acting quickly on any change you notice. Early detection remains the single biggest factor in how well treatment goes.

Further reading