Aromasin

Exemestane

Developed to target oestrogen production and indicated to support cancer treatment, this inhibitor is utilized to address hormone-sensitive malignancies.

Active ingredient
Exemestane
Supply
Rx
Route
Oral use
Form
Tablet
Strengths
25mg

Aromasin details

Condition
Breast Cancer
Therapeutic class
Aromatase inhibitor
Pharmacological class
Steroidal aromatase inactivator
Minor side effects
hot flushes; fatigue; nausea
Moderate side effects
insomnia; arthralgia; alopecia
Dosage forms
Tablet
Administration route
Oral use
Supply category
Prescription only (specially controlled medicine)
Manufacturer
Pfizer
Onset Time
2–3 days
Duration
daily
Storage instructions
Store at room temperature, out of reach of children.
Drug interactions
oestrogen-containing therapies; st. john's wort
Age restrictions
Not for children.
Pregnancy and breastfeeding
Pregnancy: Contraindicated. Breastfeeding: Do not use.
Contraindications

pre-menopausal endocrine status; hypersensitivity to exemestane; severe renal impairment; severe hepatic impairment

Precautions and warnings

monitor bone mineral density; regular blood monitoring required; not for pre-menopausal women

Serious side effects

osteoporosis, requires immediate medical attention; pathological fractures, requires immediate medical attention; severe hepatitis, requires immediate medical attention

Patient summary

Developed to target oestrogen production and indicated to support cancer treatment, this inhibitor is utilized to address hormone-sensitive malignancies.

Mechanism of action

Exemestane is a steroidal aromatase inactivator that prevents the conversion of androgens into oestrogens in peripheral tissues. By reducing circulating oestrogen levels, it inhibits the growth of hormone-dependent breast carcinoma.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Aromasin

Aromasin contains exemestane, an aromatase inhibitor used in the treatment of breast cancer. Manufactured by Pfizer, this medication works by lowering oestrogen levels in the body. It is supplied as a 25mg tablet. This therapy is intended for use under the guidance and monitoring of a medical professional.

Aromasin availability in Asia

Aromasin is registered across 14 markets including Hong Kong, Thailand and Malaysia, with availability also in the Philippines, Indonesia and Taiwan. Access to this medication can be challenging for those living in or travelling through the region, particularly when local inventory is inconsistent. Patients finding it difficult to source exemestane locally are encouraged to ensure they maintain continuous support through their primary oncology team.