Afinitor
Developed to target cancer cells to support tumour growth suppression.
- Category
- Oncology Support
- Active ingredient
- Everolimus
- Supply
- Rx
- Route
- Oral use
- Form
- Tablet
- Strengths
- 5 · 10mg
Afinitor details
- Conditions
- Renal Cell Carcinoma · Breast Cancer · Neuroendocrine Tumours
- Therapeutic class
- MTOR Inhibitor
- Pharmacological class
- Antineoplastic Agent
- Contraindications
- hypersensitivity to everolimus; hypersensitivity to sirolimus
- Precautions and warnings
- monitor blood glucose; risk of infection; regular blood count monitoring
- Minor side effects
- stomatitis; fatigue; rash
- Moderate side effects
- infections; pneumonitis; anaemia
- Dosage forms
- Tablet
- Administration route
- Oral use
- Patient summary
- developed to target cancer cells to support tumour growth suppression.
- Supply category
- Prescription only (specially controlled medicine)
- Manufacturer
- Novartis
- Onset Time
- varies per patient
- Duration
- 24 hours
- Storage instructions
- Store below 25°C. Protect from light.
- Drug interactions
- cytochrome p450 inhibitors; grapefruit
- Pregnancy and breastfeeding
- Pregnancy: must not be used. Breastfeeding: must not be used.
Serious side effects
interstitial lung disease, requires immediate medical attention; severe infections, requires immediate medical attention
Mechanism of action
Everolimus is a serine-threonine kinase inhibitor that acts as an mTOR inhibitor, reducing tumour cell proliferation and angiogenesis.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Afinitor
Afinitor contains everolimus, a medication used to treat renal cell carcinoma, breast cancer and neuroendocrine tumours. Manufactured by Novartis, this product is supplied as tablets in 5mg and 10mg strengths.
Afinitor availability in Asia
Afinitor is registered across 14 markets including Indonesia, Taiwan and South Korea, with availability also in Japan, the UAE and Singapore. Generic everolimus often provides an affordable alternative to the original brand for patients located far from a major pharmacy. This specialised medication is best used under a doctor’s care.