Pentasa

Mesalazine

Indicated to manage inflammatory bowel disease, developed to alleviate intestinal inflammation.

Active ingredient
Mesalazine
Supply
Pharmacy
Route
Oral use
Form
Prolonged-release tablet
Strengths
400mg

Pentasa details

Alternative names
Salofalk
Therapeutic class
5-Aminosalicylic Acid Derivative
Pharmacological class
Aminosalicylate
Precautions and warnings
monitor renal function; may cause blood dyscrasias
Minor side effects
headache; abdominal pain; diarrhoea; nausea
Moderate side effects
rash; fever; alopecia
Dosage forms
Prolonged-release tablet
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Ferring Pharmaceuticals
Onset Time
1–2 weeks
Duration
24 hours
Storage instructions
Store below 25°C.
Drug interactions
azathioprine; mercaptopurine
Pregnancy and breastfeeding
Pregnancy: Use with caution. Breastfeeding: Use with caution; monitor infant.
Contraindications

hypersensitivity to salicylates; severe renal impairment; severe hepatic impairment

Serious side effects

nephrotoxicity, requires immediate medical attention; blood dyscrasias, requires immediate medical attention

Patient summary

Indicated to manage inflammatory bowel disease, developed to alleviate intestinal inflammation.

Mechanism of action

Mesalamine is an aminosalicylate that acts locally in the gastrointestinal tract, inhibiting the production of prostaglandins and leukotrienes, which reduces mucosal inflammation in conditions like ulcerative colitis.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Pentasa

Pentasa contains mesalazine, an active ingredient used to manage conditions such as ulcerative colitis and Crohn’s disease. The same medication is also sold under the brand name Salofalk, which is supplied as a 400mg tablet. Manufactured by Ferring Pharmaceuticals, this treatment is designed to assist with the management of chronic inflammation in the digestive tract.

Buying Pentasa online

Pentasa is registered across 14 markets including Indonesia, Taiwan and South Korea, with availability also in Japan, the UAE and Singapore. For expats or residents living far from established supply chains, ordering this medication online is a reliable way to maintain consistent therapy across the region. Generic mesalazine often serves as a more affordable alternative to the original branded product for those managing long-term gut health.