Asacol

Mesalazine

Indicated for ulcerative colitis and formulated to mitigate inflammation.

Active ingredient
Mesalazine
Supply
Pharmacy
Route
Oral use
Form
Gastro-resistant tablet
Strengths
400mg

Asacol details

Alternative names
Octasa; Salofalk; Mezavant
Therapeutic class
Aminosalicylate
Pharmacological class
Anti-inflammatory
Known off-label uses
crohn's disease
Minor side effects
headache; nausea; diarrhoea
Moderate side effects
rash; abdominal pain; arthralgia
Dosage forms
Gastro-resistant tablet
Administration route
Oral use
Patient summary
Indicated for ulcerative colitis and formulated to mitigate inflammation.
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Tillotts Pharma
Onset Time
1–2 weeks
Duration
Ongoing treatment
Storage instructions
Store below 25°C in a dry place.
Drug interactions
azathioprine; mercaptopurine
Age restrictions
Consult physician for use in children.
Pregnancy and breastfeeding
Discuss with doctor; generally considered safe but monitoring advised.
Contraindications

hypersensitivity to salicylates; severe renal impairment; severe hepatic impairment

Precautions and warnings

monitor renal function periodically; use with care in patients with active peptic ulcer

Serious side effects

nephrotoxicity, requires immediate medical attention; blood dyscrasias, requires immediate medical attention

Mechanism of action

Mesalazine exerts a local anti-inflammatory effect on the intestinal mucosa, likely by inhibiting cyclooxygenase and lipoxygenase, thereby decreasing the production of prostaglandins and leukotrienes.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Asacol

Asacol is a recognised brand of mesalazine, widely used in the management of ulcerative colitis. The same active ingredient is also available under the brand names Octasa, Salofalk and Mezavant. Supplied as a tablet in 400mg strengths, this medication is developed by Tillotts Pharma to help patients maintain consistent treatment protocols.

Buying Asacol online

Asacol is registered across 14 markets including the Philippines, Indonesia and Taiwan, with availability also in South Korea, Japan and the UAE. As one of the most frequently ordered medications for ulcerative colitis across the region, it is often secured online with delivery across these locations. Generic mesalazine, much of it produced in India, offers a far more affordable alternative to the original brand, helping expats and patients further afield maintain continuity of care.