Azulfidine

Sulfasalazine

Indicated to manage chronic inflammatory conditions to alleviate symptoms and reduce tissue inflammation.

Active ingredient
Sulfasalazine
Supply
Rx
Route
Oral use
Form
Tablet
Strengths
500mg

Azulfidine details

Alternative names
Salazopyrin
Therapeutic class
Disease-modifying antirheumatic drug (DMARD)
Pharmacological class
Sulfonamide
Minor side effects
headache; nausea; loss of appetite
Moderate side effects
rash; fever; anaemia
Dosage forms
Tablet
Administration route
Oral use
Supply category
Prescription only (specially controlled medicine)
Manufacturer
Pfizer
Onset Time
1–2 weeks
Duration
24 hours
Storage instructions
Store at room temperature away from sunlight and moisture.
Drug interactions
digoxin; folic acid
Age restrictions
Use with caution in elderly patients.
Contraindications

hypersensitivity to sulfonamides or salicylates; intestinal or urinary obstruction; porphyria; severe hepatic or renal impairment

Precautions and warnings

maintain adequate fluid intake to prevent crystalluria; regular blood count monitoring is essential; may cause temporary orange discolouration of body fluids

Serious side effects

blood dyscrasias, requires immediate medical attention; stevens-johnson syndrome, requires immediate medical attention; hepatitis, requires immediate medical attention

Patient summary

Indicated to manage chronic inflammatory conditions to alleviate symptoms and reduce tissue inflammation.

Mechanism of action

The active substance exerts anti-inflammatory and immunomodulatory effects within the gastrointestinal tract and synovial joints by inhibiting prostaglandin synthesis and inflammatory mediator release.

Pregnancy and breastfeeding

Pregnancy: Consult a specialist; use only if benefit outweighs risk. Breastfeeding: Use with caution as it is excreted in breast milk.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Azulfidine

Azulfidine, manufactured by Pfizer, contains the active ingredient Sulfasalazine. It is used in the treatment of Rheumatoid Arthritis, Ulcerative Colitis and Crohn’s Disease. This medication is also sold under the brand name Salazopyrin. It is provided in tablet form with a strength of 500mg.

Buying Azulfidine online

Azulfidine is registered across 13 markets, including the UAE, Singapore and Hong Kong, with availability also in Thailand, Malaysia and the Philippines. Generic Sulfasalazine, much of it produced in India, offers a far more affordable alternative to the original brand. This is a practical solution for expats and those living without easy access to a pharmacy who need regular access to treatment for their health conditions.