Methotrexate Tablets
Utilized to manage autoimmune responses and indicated to alleviate inflammation-related tissue damage effectively.
- Categories
- Oncology Support · Autoimmune Support
- Active ingredient
- Methotrexate
- Supply
- Rx
- Route
- Oral use
- Form
- Tablet
- Strengths
- 2.5mg
Methotrexate Tablets details
- Conditions
- Rheumatoid Arthritis · Psoriasis · Crohn's Disease
- Alternative names
- Maxtrex
- Therapeutic class
- Antimetabolite
- Pharmacological class
- Folic acid antagonist
- Contraindications
- severe hepatic impairment; pregnancy; breastfeeding; severe renal impairment
- Precautions and warnings
- regular blood monitoring required; photosensitivity precaution
- Minor side effects
- nausea; abdominal pain; fatigue
- Moderate side effects
- stomatitis; elevated liver enzymes
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription only (specially controlled medicine)
- Manufacturer
- Hospira
- Onset Time
- 3–6 weeks
- Duration
- long-term
- Storage instructions
- Store at room temperature in a safe place.
- Drug interactions
- alcohol; nsaids; salicylates
- Age restrictions
- Use with caution in elderly patients.
- Pregnancy and breastfeeding
- Pregnancy: absolute contraindication. Breastfeeding: contraindicated.
Serious side effects
bone marrow suppression, requires immediate medical attention; hepatotoxicity, requires immediate medical attention
Patient summary
Utilized to manage autoimmune responses and indicated to alleviate inflammation-related tissue damage effectively.
Mechanism of action
Methotrexate inhibits dihydrofolate reductase, thereby interfering with DNA synthesis and cellular replication to suppress overactive immune responses in chronic inflammatory conditions.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Methotrexate Tablets
Methotrexate Tablets contain methotrexate, which is used for the management of Rheumatoid Arthritis, Psoriasis and Crohn’s Disease. This active ingredient is also marketed as Maxtrex. The medication is supplied as a tablet in the 2.5mg strength and is produced by manufacturers such as Hospira.
Methotrexate Tablets availability in Asia
Methotrexate Tablets are registered across 14 markets including the Philippines, Indonesia and Taiwan, with availability also in South Korea, Japan and the UAE. Generic versions of this medication, often sourced from India, provide a more affordable alternative to the original brand, supporting access for expats and patients living far from a standard medical supplier. This treatment is potent and should only be used under the direct supervision of a doctor.