Neoral
This medication is intended to support the immune system and is indicated to alleviate risks associated with organ transplant rejection.
- Category
- Autoimmune Support
- Active ingredient
- Ciclosporin
- Supply
- Rx
- Route
- Oral use
- Form
- Capsule, soft
- Strengths
- 25 · 100mg
Neoral details
- Conditions
- Transplant Rejection · Rheumatoid Arthritis · Psoriasis
- Alternative names
- Capimune
- Therapeutic class
- Immunosuppressant
- Pharmacological class
- Calcineurin inhibitor
- Minor side effects
- tremor; fatigue; nausea
- Moderate side effects
- hypertension; hirsutism; renal impairment
- Dosage forms
- Capsule, soft
- Administration route
- Oral use
- Supply category
- Prescription only (specially controlled medicine)
- Manufacturer
- Novartis
- Onset Time
- 1–2 weeks
- Duration
- Continuous
- Storage instructions
- Store at room temperature below 25°C.
- Drug interactions
- grapefruit; st. john's wort; tacrolimus; ketoconazole
- Age restrictions
- Dose adjustment required for children.
- Pregnancy and breastfeeding
- Pregnancy: Use only if strictly necessary. Breastfeeding: Not recommended.
Contraindications
hypersensitivity to cyclosporine; uncontrolled hypertension; malignancy; impaired renal function
Precautions and warnings
requires regular monitoring of blood levels; avoid excessive sun exposure; do not substitute with generic cyclosporine without advice
Serious side effects
nephrotoxicity, requires immediate medical attention; skin malignancy, requires immediate medical attention
Patient summary
This medication is intended to support the immune system and is indicated to alleviate risks associated with organ transplant rejection.
Mechanism of action
Cyclosporine is a potent immunosuppressive agent that selectively inhibits the production and release of interleukin-2 by T-lymphocytes. This blocks the activation of T-cells, preventing the body from rejecting transplanted organs and suppressing autoimmune activity.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Neoral
Neoral is the established brand of Ciclosporin, used primarily in the management of Transplant Rejection, Rheumatoid Arthritis and Psoriasis. The same active ingredient is also sold as Capimune. Manufactured by Novartis, this medication is produced as a tablet in 25mg and 100mg strengths.
Neoral availability in Asia
Neoral is registered across 14 markets throughout the region, including the UAE, Singapore and Hong Kong, with availability also in Thailand, Malaysia and the Philippines. Generic Ciclosporin, much of it sourced from manufacturing hubs in India, offers a more affordable alternative for patients requiring long term therapy far from their typical clinic. This specific medication is intended to be used strictly under a doctor’s care given the complexity of the underlying conditions.