Crohn’s Disease

Crohn’s disease is a long-term inflammatory condition affecting the digestive tract. Unlike ulcerative colitis, which is confined to the colon, Crohn’s can strike anywhere from the mouth to the rectum, though the small intestine and colon are the most common sites. It follows a pattern of flares and remission that can last years.

Medicines used to treat Crohn's Disease

Azulfidine

Sulfasalazine

500mg

Indicated to manage chronic inflammatory conditions to alleviate symptoms and reduce tissue inflammation.

From $0.85 / tablet View

Pentasa

Mesalazine

400mg

Indicated to manage inflammatory bowel disease, developed to alleviate intestinal inflammation.

From $1.32 / tablet View

Methotrexate Tablets

Methotrexate

2.5mg

Utilized to manage autoimmune responses and indicated to alleviate inflammation-related tissue damage effectively.

From $0.73 / tablet View

What flares feel like

During active disease, the hallmark symptoms are cramping abdominal pain, frequent loose stools (sometimes with blood), and persistent fatigue. Weight loss is common during prolonged flares because the inflamed gut absorbs nutrients poorly. Some people develop mouth ulcers, joint pain, or skin changes alongside gut symptoms, reflecting Crohn’s broader autoimmune character.

Medicines used in management

There is no cure, but treatment can achieve and maintain remission. Aminosalicylates such as mesalazine and sulfasalazine reduce mucosal inflammation and are among the most-used agents. For disease that does not respond to aminosalicylates, methotrexate is an established option that dampens the immune response driving gut damage. Nutritional support and a low-residue diet during flares can also ease symptoms. Full digestive health management often combines medication with dietary and lifestyle adjustments.

Seek urgent medical attention if you develop a high fever, severe abdominal pain that comes on suddenly, or signs of obstruction such as persistent vomiting with no bowel movements.