Compazine
Intended to mitigate nausea and vomiting and to target the vestibular system to manage vertigo-related symptoms.
- Category
- Digestive Health
- Active ingredient
- Prochlorperazine
- Supply
- Rx
- Route
- Oral use
- Form
- Tablet
- Strengths
- 5mg
Compazine details
- Alternative names
- Stemetil
- Therapeutic class
- Phenothiazine Antipsychotic
- Pharmacological class
- Dopamine Antagonist
- Known off-label uses
- anxiety
- Contraindications
- circulatory collapse; severe central nervous system depression
- Precautions and warnings
- may cause drowsiness; use with caution in elderly patients
- Minor side effects
- drowsiness; dizziness; dry mouth
- Moderate side effects
- extrapyramidal symptoms; tachycardia; blurred vision
- Dosage forms
- Tablet
- Administration route
- Oral use
- Supply category
- Prescription only (specially controlled medicine)
- Manufacturer
- Sanofi
- Onset Time
- 30–60 minutes
- Duration
- 4–6 hours
- Storage instructions
- Keep at room temperature.
- Drug interactions
- alcohol; sedatives; opioids
- Age restrictions
- Not recommended for children under 2 years.
Serious side effects
neuroleptic malignant syndrome, requires immediate medical attention; tardive dyskinesia, requires immediate medical attention; agranulocytosis, requires immediate medical attention
Patient summary
intended to mitigate nausea and vomiting and to target the vestibular system to manage vertigo-related symptoms.
Mechanism of action
Prochlorperazine acts centrally by blocking dopamine receptors in the brain's chemoreceptor trigger zone. This action suppresses the signaling pathway that triggers nausea and vomiting reflexes.
Pregnancy and breastfeeding
Should be avoided during pregnancy unless clearly necessary. Breastfeeding: May be used if clinically indicated; monitor infant.
Where this medicine is registered
- Singapore
- Hong Kong
- Thailand
- Malaysia
- Philippines
- Indonesia
- Taiwan
- South Korea
- Japan
- Australia
- New Zealand
- UAE
- South Africa
About Compazine
Compazine is a recognised brand of prochlorperazine, a medication used to treat nausea, vomiting and vertigo. The same active ingredient is also sold under the brand name Stemetil, supplied as a tablet in a strength of 5mg. Manufactured by Sanofi, it remains a primary choice for managing symptoms associated with inner ear disturbances or related ailments.
Buying Compazine online
Compazine is registered across 13 markets including Hong Kong, Thailand and Malaysia, with availability also in the Philippines, Indonesia and Taiwan. It is one of the most ordered medications for expats throughout the region, offering a consistent solution for those living in areas with limited local stock. Generic prochlorperazine, much of it made in India, is far more affordable than the original brand, making it a practical choice for patients who need access to these specific tablets away from home.