Motilium

Domperidone

Indicated to address digestive upset, this product is designed to target gastric motility and intended to support comfortable digestion.

Active ingredient
Domperidone
Supply
Pharmacy
Route
Oral use
Form
Film-coated tablet
Strengths
10mg

Motilium details

Conditions
Nausea · Vomiting
Therapeutic class
Antiemetic
Pharmacological class
Dopamine Antagonist
Contraindications
severe hepatic impairment; cardiac conduction disorders
Precautions and warnings
use lowest effective dose for shortest duration
Minor side effects
dry mouth
Moderate side effects
headache; diarrhoea; anxiety
Dosage forms
Film-coated tablet
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Janssen
Onset Time
30–60 minutes
Duration
4–8 hours
Storage instructions
Store at room temperature in original packaging.
Drug interactions
antacids; qt prolonging agents
Age restrictions
Avoid in infants; use caution in elderly.
Pregnancy and breastfeeding
Consult doctor; generally avoided unless essential.
Serious side effects

arrhythmia, requires immediate medical attention; sudden cardiac death, requires immediate medical attention

Patient summary

Indicated to address digestive upset, this product is designed to target gastric motility and intended to support comfortable digestion.

Mechanism of action

This agent acts as a peripheral dopamine antagonist. It speeds up gastrointestinal transit and blocks dopamine receptors in the chemoreceptor trigger zone to prevent feelings of nausea.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Motilium

Motilium is a widely recognised brand name for domperidone, used to manage symptoms of nausea and vomiting. Janssen produces this treatment as a standard 10mg tablet. Medications containing this active ingredient work by assisting movement in the upper gastrointestinal tract to help relieve persistent discomfort, offering a solution for those seeking support for these conditions.

Buying Motilium online

Motilium is registered across 14 markets including the UAE, Singapore and Hong Kong, with availability also in Thailand, Malaysia and the Philippines. Generic domperidone, much of which is made in India, provides a cost-effective alternative to the original brand for expats and residents across the region. Such options remain among the most ordered items on our platform by patients located far from local medical retailers who require reliable delivery to their door.