Lodine

Etodolac

Indicated to alleviate pain and inflammation in chronic musculoskeletal conditions to support mobility.

Active ingredient
Etodolac
Supply
Pharmacy
Route
Oral use
Form
Tablet; Capsule, hard
Strengths
200 · 300 · 400mg

Lodine details

Alternative names
Etopan
Therapeutic class
Non-steroidal anti-inflammatory drug (NSAID)
Pharmacological class
Pyranoindole acetic acid
Known off-label uses
ankylosing spondylitis
Minor side effects
nausea; dyspepsia; dizziness; headache
Moderate side effects
fluid retention; abdominal pain; constipation; flatulence
Dosage forms
Tablet; Capsule, hard
Administration route
Oral use
Supply category
Pharmacist only, dispensed without a prescription
Manufacturer
Wyeth
Onset Time
30–60 minutes
Duration
4–8 hours
Storage instructions
Store below 25°C in a dry place.
Drug interactions
warfarin; lithium; alcohol
Age restrictions
Not for use in children.
Contraindications

hypersensitivity to etodolac; active peptic ulceration; history of asthma triggered by aspirin; severe heart failure

Precautions and warnings

use with caution in elderly patients; monitor blood pressure regularly; risk of gastrointestinal bleeding

Serious side effects

gastrointestinal haemorrhage, requires immediate medical attention; myocardial infarction, requires immediate medical attention

Patient summary

indicated to alleviate pain and inflammation in chronic musculoskeletal conditions to support mobility.

Mechanism of action

Etodolac works by inhibiting the enzymes cyclooxygenase-1 and cyclooxygenase-2, which are responsible for the synthesis of prostaglandins that mediate pain and inflammation.

Pregnancy and breastfeeding

Pregnancy: Avoid, particularly in the third trimester. Breastfeeding: Not recommended.

Where this medicine is registered

  • Singapore
  • Hong Kong
  • Thailand
  • Malaysia
  • Philippines
  • Indonesia
  • Taiwan
  • South Korea
  • Japan
  • Australia
  • New Zealand
  • UAE
  • South Africa

About Lodine

Lodine is a brand of etodolac, a non-steroidal anti-inflammatory drug used for the management of pain and inflammation associated with conditions such as osteoarthritis and rheumatoid arthritis. The same active ingredient is also sold under the name Etopan. This medication is supplied as a tablet, available in strengths of 200mg, 300mg and 400mg.

Buying Lodine online

Lodine is registered across 13 markets, including Thailand, Malaysia and the Philippines, with further availability in Indonesia, Taiwan and South Korea. Generic versions of etodolac, often manufactured in India, remain a highly affordable alternative to the original version produced by Wyeth. For many expats and residents living in regions where a reliable supply is difficult to find, ordering online offers a consistent way to maintain access to this treatment.